Keep on trying. Keep searching. Keep asking docs to try something else.
I got good relief from my first spinal injection, then I was in a wreck and it all got worse. Subsequent injections gave no relief or not enough for a long enough time. Recently the pain doc gave me a caudal injection which was wonderful. It hurt for a week, but the sciatica is gone again. He had just asked me if I was ready for surgery, and I had replied, not yet, so he tried the caudal. Tramadol dulls my disc pain, but doesn't make it tolerable by itself. I take Vicodin after surgery, but get used to it after a couple of weeks.
I've got shoulder impingement with bone spurs. I had physical therapy which made it worse. Three injections were wonderful, but they only lasted a few weeks. I can't have surgery that's been recommended by two docs for a few months, because I have to have sinus surgery next week. I kept on searching for exercises and found one where I turn my hand palm up and atraighten my arm and pull it back a little. It turns the head of the humerus (long bone in the upper arm) and stops the pain. It only works for a little while, but I can live with that because it keeps on working when I do it.
I've tried every medicine for fibromyalgia muscle pain, some twice and am currently getting a little relief with tramadol. It's better if I take it with Tylenol. I tried stronger meds, but they don't work for me on the muscle pain. My doc recently gave me Topamax. I'm trying it, but at a half dose because I'm scared of it. So far I can't see it does anything at all.
I'm not quitting. There are combinations of meds and treatments I haven't tried yet.