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Regular Member

Date Joined Dec 2009
Total Posts : 103
   Posted 7/1/2011 2:51 PM (GMT -6)   
Anyone know why ibuprofen works better on my pain (3 pills at a time) then my Hydroco (lortab) does? I just don't understand it.

Forum Moderator

Date Joined Feb 2003
Total Posts : 16757
   Posted 7/1/2011 2:59 PM (GMT -6)   
If the pain is caused by inflammation the Ibuprophen will work better. I fell and broke my arm two years ago, I had Dilaudid to take for pain, it did nothing for my pain. My neighbor is an RN and he came over to check on me and I was griping that the pain medication had no effect on my pain, he said I will be right back. He came back with Ibuprophen and that is what kept my pain level down with a broken arm. He said I had a lot of inflammation going on with the break and he was right, it worked great for me. I stopped the Dilaudid completely.
Moderator Chronic Pain Forum

Veteran Member

Date Joined Jan 2010
Total Posts : 3557
   Posted 7/1/2011 3:19 PM (GMT -6)   
Yep...totally agree with Straydog...I had the same thing with a toothache....antibiotics and an Advil did the best to take care of the pain...

Or when I get a headache...I will take Acetaminophen and it helps with that type of pain...

Opiates hit receptors in our brain that kind of just 'dulls' the sensation of pain....along with making us 'not care as much' about that a way to describe it...

Another example is when I had more nerve pain before my last surgery...My opiates do not help much for that but specific nerve pain medicine, like Cymbalta (there is Lyrica and Neurontin also) worked for this.

One more is for muscle pain...I take a Flexeril when needed for this specific pain after hiking, or sore after walking my dog (he's 75 pounds and can pull sometimes on the leash)...'s really about working with your Dr. to figure out what is causing the pain, or what 'type' of pain it is, and then using specific/targeted medicine....along with other modailities, to help manage it...

Glad to hear that Ibuprofen is working well for you!!
SB and "the pup who snores loudly" 
ACDF C5-C7, (no hardware), with autograft bone Nov. 2001
(reabsorption of bone 2 years later...still lost in body..expect to burp it out at anytime..haha")) 
ACDF with hardware, allograft bone Nov. 2005 
Anterior and Posterior CDF, allograft bone with BMP, removal of old hardware, use of titanium plates, rods, screws, & kitchen sink (lol) Oct 2006

Regular Member

Date Joined Dec 2009
Total Posts : 103
   Posted 7/1/2011 3:24 PM (GMT -6)   
I am currently being treated for rheumatoid arthritis and fibromyalgia.

My chronic pain is in my muscles. They tighten up and just hurt too much to move. The slightest movement of my legs will hurt the muscles in my legs from toe to knee, everywhere.

My entire body goes through the muscle pain. I have been checked for muscle diseases and it came out negative.

Guess I just need to find out why my muscles inflame.

Thank you so much for the information.

God bless.

Veteran Member

Date Joined Mar 2011
Total Posts : 816
   Posted 7/1/2011 6:40 PM (GMT -6)   
Hello, omg, finally the question I have been asking myself for many years is answered.  I have been on narcotic pain meds for more than 11 years, I have never been able to understand why these drugs help with the chronic pain in my back, right leg, and various other hurts.
The thing is when I have a headache, I still reach for acetaminophen, xtra strenght and away goes my headache.  Most of my headaches come when I have a sinus infection, which I just finished taking the last of my z-pack, oh sorry forgot to say I had a sinus infection.
Ok time for me to sign off,  thanks again shanbr for asking the question, and thanks to everyone else for responding, and giving me an answer.
Hope all are having low pain day now and for a long, long, long time.
degenerative disc disease, fibromyalgia, osteoarthritis, neuropathy, lumbar laminectomy july 1998 no help, rechargeable neurostimulator unit low right back w/lead wires to left side and right leg unit not working just sitting there.i am 57 years young in may will turn 58. i have 2 grown daughters, 25 and 29. i have 2 grandchildren, 9 year old grandaughter and 5 yr. old grandson

Veteran Member

Date Joined Oct 2009
Total Posts : 5028
   Posted 7/2/2011 12:23 PM (GMT -6)   
Yup, it makes all the difference what's CAUSING the pain.

Tramadol dulls my fibro muscle pain but does nothing for my sinus headaches and bone spurs in my shoulder (impingement). Ibuprofen helps that some unless I lift my arm or roll on it. Hydrocodone dulls the shoulder and helps fairly well with post surgery pain. Tylenol doesn't do anything for inflammation, but dulls shoulder when it's not time for anything else.

None of them are perfect, and the long-lasting versions I have tried don't work as well for me.

Today I think I may have caught a cold from grandkids on top of the sinus infection I have continuing after sinus surgery. All causing awful drainage and nausea. I was already still having trouble breathing, landed in ER when albuteral inhaler triggered tachycardia that wouldn't stop for hours. Today I added Nexium for nausea to the Zofran, which wasn't doing enough - all Rx'd and consulted as usual. Of course the extra strain kicks the fibro up a notch.
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