I just got prescribed Opana today, so I'll post is any effects come out in the next few days. But honestly, I could talk with my doctor and say the side effects are a big turn off. He or she should be able to help, be it with medicines to counter the side effects or switching you to a new medicine. I was talking Butran patches, but after my doctor upped my dose, anxiety from the patch increased greatly, so we talked and I got switched to Opana ER. I'm headed in on the 11th to talk things over, but she was very willing to work with me over the phone before then so I didn't have to live in pain, I hope your doctor is willing to do a similar thing.