Hello drjimmy! I have been on Percocet and Nucynta, so I will give you the results that I had...I had been on and off Percocet for almost 10 years due to the many surgeries I have had. When I started taking it for my chronic pain issues I found that the dosage had to be increased several times. After being on the Percocet 10/325 for a while and it not really helping me any longer my pain doctor put me on Nucynta 75. I did that for a couple of weeks and it did help more than the Percocet, but it's relief only lasted 2-3 hours. So, I was put on the extended release 100 to take every twelve hours and the regular 75 to take for breakthrough pain. I have found this to be pretty effective and much more effective than the Percocet. However, my pain has been really bad recently and the Nucynta is barely touching the pain...I see my pain doctor on Monday and will be discussing this with him.
I have not really had any side effects except for the regular Nucynta making me sleepy sometimes. I've also read that there are more side effects with it than with Percocet, but that has not been the case for me.
I hope your father-in-law gets some relief from the Nucynta...Keep us posted.
Current: Lumbosacral Spondylolysis, Lumbosacral Neuritis, Arthritis L3-S1, Facet Syndrome, SI Joint Dysfunction, Interstitial Cystitis, Vulvodynia, Restless Leg Syndrome, Bi-polar, IBS, Fibromyalgia, PTSD. On too many medication's to list & have had many surgeries & procedures and I'm only 34.