Just wanted to add my feedback to the Patch. a few hours into the patch, it seem to reduce my pain as I mention above, but over night, little more than about 12 hours, when I woke up, I was in so much pain, I can not get out of my bed, mainly pain in the upper leg and back. also, the side effects got so bad, I was so dizzy and nausea, I can not stand still. I had to remove the patch and gone back to sleep for a couple of hours. the dizziness and nausea was reduce dramatically. even on the lowest dose, I was having so much problems. anyway, hope it works for other people better.