Two supplements for nerve pain and inflammation - Curamin and Krill Oil

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Sue123
Regular Member


Date Joined Nov 2011
Total Posts : 52
   Posted 12/17/2011 1:23 AM (GMT -6)   
A discussion is happening on the Fibromyalgia forum on the supplements Curamin and Krill oil. Both are helping with chronic pain and inflammation. I thought I would list a summary and a copy of my comments below for those interested in reading more about it.

The members are finding Krill oil reduces nerve pain and the amount of pain medicine needed. Curamin has reduced the amount of pain, and their blood sugars have improved to such an extent as to reduce the amount of insulin needed. Here's an article on Curamin....
http://www.greenpatriotism.com/?page_id=470

My thoughts.....

Curamin contains DLPA (DL-Phenylalanine), Boswellia, Curcumin, and Nattokinase. It looks like a great supplement to include all four supplements that help pain and inflammation! I noticed their site doesn't mention whether to take with food. Since DLPA is an amino acid, it's best to take it on an empty stomach with water or juice about an hour before meals to be most effective. If you want to take increased quantities of any individual ingredient, than it may be worthwhile to look at buying them separately. It's possible it may also save money.

I take 1500 mg of DLPA separately, and find it really helps. DLPA is made up of D-Phenylalanine which helps pain and L-Phenylalanine which helps depression. The D is synthetic and the L is natural. Since my depression is in check, I'm going to switch to the D. (thanks to Spinal Soldier who gave me more insight into it!)

I have found curcumin (i.e.turmeric spice) especially works for those who have both fibro and an inflammatory disease like asthma, diabetes, IBS or RA. Turmeric is one of the only spices that act as a glutathione precursor, and our bodies produce glutathione which helps repairs cells (and it's used as an anti-aging supplement, too!) Avocados and asparagus are the two best foods that also help in the same way as turmeric.
Here's another article on turmeric,
http://www.whfoods.com/genpage.php?tname=foodspice&dbid=78

Unfortunately for me, the supplements that work to dampen inflammation don't work for me. My fibro is focused on the central nervous system's and its interpretation of pain; so, I focus on supplements that work on the nerves alone. One of the benefits of taking the fish oil is that is helps the health of the nerves. It's works on the covering of the nerve, called the myelin sheath, which is a fatty tissue. It's sort of like the covering on an electrical cable! The myelin sheath gets attacked in auto-immune disorders and the body repairs it, which is where the fish oil comes into play. I take 3g of Minami fish oil. It's usually recommended to take 1g for heart disease, and more if you have an associated nervous system illness. For example, 3g is recommended for those with MS, ALS, and other neurological diseases. Since I believe my pain is neurologically based, I take the full 3g. A side effect is that it helps with the constipation brought on by narcotic pain killers!

For fish oil, for those trying other brands, a cheap fish oil will result in burping up a bad taste, it means the oil is rancid.; Low quality fish oils use cheap fish sources and bad processing which results in making the oil next to useless. A good fish oil also adds Vitamin E or another oil to help keep the fish oil from spoiling. After much research on processing methods and prices, I found the best one to be Minami Cardio Fish Oil. I buy it at www.iherb.com. (for first time orders, DEX579 coupon will get one $5 off). In Canada, fish oil is very expensive, and this brand has a good price point for the quality. One can likely buy it in the states off the shelf, where competition helps keep prices down!

There's also a debate between krill oil and fish oil. I heard krill oil is good as the source waters are unpolluted, but some of the health claims over the regular fish oil are disputed.
http://healthyomega3.com/krill-oil-vs-fish-oil/
Krill oil is also more expensive, too. Also, some people with shellfish allergies are allergic to krill as when it's harvested, it can contain shellfish. When looking at buying a fish oil supplement, it's important to look at the amount of Omega's, that is, DHA, EPA one is getting. The krill oil that is advertised as 1000mg, does not give you 1000mg of Omega supplements... one is ingesting 1000mg of Krill. It's a trick the companies use to sell their products, so be mindful and save your money!

Laura
Neuropathic pain since 2000, born 1960, Fentanyl, Oxycontin
Therapies: Epsom salt baths, sauna, therapeutic yoga, visualization, NLP, massage and chiropractic
Supplements: Source Naturals Multi-Vitamin, Minami Omega Fish Oil, Co-enzyme Q10 Ubiquinol, DLPA, N-Acetyl Tyrosine, Magnesium Glycinate, 3000 IU Vitamin D, Megafolonic, B12 Methylcobalamin, Magnesium Ascorbate (Vitamin C)

grainofsalt
Regular Member


Date Joined Aug 2010
Total Posts : 215
   Posted 12/17/2011 1:44 AM (GMT -6)   
DLPA sounds worth trying, especially for nueropathic pain. According to wiki's page: "Phenylalanine is a precursor for tyrosine, the monoamine signaling molecules dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), and the skin pigment melanin."

Its something I will have to consult with a pharmacist and PM doctor about first, since I take Nucynta, which is a single molecule medication that acts as both an opioid and potent norepineprine reuptake inhibitor (also has mild effect on seratonin).

What I have personally found with herbal supplements however is that their effects on nuerotransmitters and biochemicals (such as saint johns wart and kava kava) tend to be less dramatic than prescription medications.

Provided I get the green light, I'll probably do a trail of this. The reason being is that their mechanisms of action are different. One acts as a pre-cursor whereas my medication acts as a reuptake inhibitor. I kind of see it like replacing the air filter AND putting fuel injector cleaner to inprove the performance of a vehicle. Hopefully a better end result through combined means.
 
Will also inquire to ensure seratonin syndrome isn't a major risk, but this seems to only be an issue if a very large amount of the supplement is taken: "in large quantities, interferes with the production of  serotonin"

MRI revealed disc bulge and test injections revealed RA. Radio Freq procedures helped for months, but pain is up and im having the procedure done again. Currently on 75 mgs of Nucynta (tapentadol - A MOR + NRI) 2 to 3 time per day and Soma 350 as needed.

Post Edited (grainofsalt) : 12/16/2011 11:48:40 PM (GMT-7)


Chutz
Forum Moderator


Date Joined Jan 2005
Total Posts : 9255
   Posted 12/17/2011 2:19 AM (GMT -6)   
Thanks for posting this article from the Fibro Forum. Since I also have fibro it's something I've begun looking into. Sherrine's information is clear and very helpful, IMHO. She did a lot of reading and research before she tried it herself.

One thing to be careful of is the interaction between these 'natural products' and any other medication or condition you may have. The basic concerns are these I found on WebMD.com:

1) DoLevodopa is used for Parkinson's disease. Taking phenylalanine along with levodopa can make Parkinson's disease worse. . Do not take phenylalanine if you are taking levodopa.

2) Medications for depression (MAOIs) interacts with PHENYLALANINE:

Phenylalanine can increase a chemical in the body called tyramine. Large amounts of tyramine can cause high blood pressure....

3) Medications for mental conditions (Antipsychotic drugs) interacts with PHENYLALANINE:

Some medications for mental conditions might cause jerky muscle movements. Taking phenylalanine along with some medications for mental conditions might increase the risk of jerky muscle movements.

Some medications for mental conditions include chlorpromazine (Thorazine), clozapine (Clozaril), fluphe****ne (Prolixin), haloperidol (Haldol), olanzapine (Zyprexa), perphe****ne (Trilafon), prochlorperazine (Compazine), quetiapine (Seroquel), risperidone (Risperdal), thioridazine (Mellaril), thiothixene (Navane), and others.

Hope this works for anyone who cares to try it. If I do give it a go and my doctor approves I'll be sure to let you know.

Chutz
Moderator on the Fibromyalgia and Chronic Pain forums
~*~*~*~*~*~*~
Fibromyalgia, IDDM. UC, , Osteoarthritis and others slowly meandering their way through.
~~~~~
An investment in knowledge pays the best interest...Benjamin Franklin

Screaming Eagle
Veteran Member


Date Joined Sep 2009
Total Posts : 5005
   Posted 12/17/2011 3:07 AM (GMT -6)   
Just wanted to pop in and say that I'm currently on both of the OTC supplements you have spoken of here. I have been on the Krill oil for a couple of years now…..but the Curamin…I just started a couple of weeks ago. I really don't have anything to report on it yet, because I'm in the middle of a couple of scripted med changes at the moment,….but I am keeping notes on it.

One thing I do know about Sherrine…is that she does her homework! I actually bought this Curamin….and reported back to Sherrine on it….and found out I bought the wrong brand…..so I will use up what I have and seek out the exact one she recommends.

I guess this is as good time as any to mention a OTC that I have used in the past…as well as my sister. Both of us noticed changes in our pain levels…but small changes. The product is called Cobroxin….and here in the US is sold by Walgreens. At the moment …Im sick here with a chest cold…so do your own research on it.

My wife and I are always open to Homeopathic treatments….and also use others as well….like Cat's Claw….used for inflammation.

I'm…off to sleep again….just took the puppy out for the nightly chore! tongue

Take care,

SE
Moderator Chronic Pain Forum

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momtofourangels
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Date Joined Apr 2010
Total Posts : 2265
   Posted 12/17/2011 6:04 PM (GMT -6)   
I take the Cobroxin as well. Michael told me about it and I am taking it. It helps. I'm will to try anything that may help, but won't react with my prescribed meds.

I'm afraid I can't take the one that may interact with Seroquel or may cause high blood pressure, as I am being treated for that already.

Thanks for sharing the information about these.

hugs
Loretta
Dx: osteoarthritis, bursitis in left hip, Osteoarthrits in right hip, compression fracture in thoracic spine due to falling on frozen ground March 2001 , ddd, spinal stenosis, bone spurs, osteoarthritis in spine, osteoarthritis in both knees
Meds: Fentanyl patch, oxycodone, otc: BenGay, Tylenol Arthritis on occasion

CRPSpatient
Veteran Member


Date Joined Mar 2011
Total Posts : 1276
   Posted 12/18/2011 3:20 AM (GMT -6)   
Hi Laura,

Thank you so much for posting about this. I might just start looking into it for myself too - not sure how much if anything you know about CRPS, but that too is related to how the central nervous system interprets and processes pain signals. I think there are probably more than a few similarities between Fibromyalgia and CRPS - certainly a number of CRPS patients seem to develop Fibro subsequently.

I suspect that a good quality essential fatty acid supplement, be it fish oil, flax seed oil or whatever, is probably crucial to any of us with neuropathic pain because of the very reasons you've mentioned.

I noticed that you mentioned avocados in your original post too. There is a product called Avosoy, which contains avocado and soybean oil. My Mum started taking it on the advice of her GP and pharmacist -she has osteoarthritis in her knees and spine and was needing daily ibuprofen. She was able to cut out the NSAIDs entirely after about a month on the Avosoy.

Laura
Moderator - Chronic Pain Forum

Full body CRPS with spasms, dystonia & contractures, gastroparesis, orthostatic hypotension,bradycardia/tachycardia, bursitis, CTS, osteoporosis, multiple compression fx, disc bulges.

Oxycodone ER/IR, Topamax, Mobic, Somac, Cipramil, Midodrine, Vit D & C, SCS, baclofen/bupivacaine pump

tmjpain
Veteran Member


Date Joined Oct 2008
Total Posts : 2024
   Posted 12/18/2011 12:11 PM (GMT -6)   
I will be going to the health food store this week to get some Curemin. Wouldn't that be great if it helped me. I will do some reading on the Avasoy and krill oil. I do take Omega 3 capsules so perhaps that is much the same.

Thank you for the info. If anyone has positive results taking the curemin it would be great if you could post and let us know.

Suzane

Screaming Eagle
Veteran Member


Date Joined Sep 2009
Total Posts : 5005
   Posted 12/18/2011 2:15 PM (GMT -6)   
Suzane…make sure you follow Sherrine's advice on which brand you get….as she believes that not all of them are effective,…and can be a waste of money. She told me which one…but I have it tucked away in a folder somewhere…and will have to pull it out again for review. I told her the one I bought…and she said not even close!….so be careful in your purchase.

Good Luck!

SE
Moderator Chronic Pain Forum

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Chartreux
Veteran Member


Date Joined Aug 2006
Total Posts : 9664
   Posted 12/18/2011 3:22 PM (GMT -6)   
I think the thing with fish oil is to also look for one that filters out pcb's....
PCB is still around and in fish, so do your homework on finding a good
Omega-3 fish oil...I get Lovaza, it's a script, but you need to make
sure your medication plans will cover Lovaza, and fish oil should be refrigerated....

But with anything look this stuff up and then ask your doctor about starting it
to see, if it's not going to mix bad with any medications your already taking.
and the saying "What works for me, might not help everyone..." but sometimes
these things are worth a try...just ask your doctor first....

Sue123
Regular Member


Date Joined Nov 2011
Total Posts : 52
   Posted 12/19/2011 3:27 AM (GMT -6)   
SE, no need to find that paper, there's only one brand of Curamin as it's a proprietary blend by Terry Naturally...iherb.com has competitive pricing
http://www.curamin.com/
Laura
Neuropathic pain since 2000, born 1960, Fentanyl, Oxycontin
Therapies: Epsom salt baths, sauna, therapeutic yoga, visualization, NLP, massage and chiropractic
Supplements: Source Naturals Multi-Vitamin, Minami Omega Fish Oil, Co-enzyme Q10 Ubiquinol, DLPA, N-Acetyl Tyrosine, Magnesium Glycinate, 3000 IU Vitamin D, Megafolonic, B12 Methylcobalamin, Magnesium Ascorbate (Vitamin C)

Screaming Eagle
Veteran Member


Date Joined Sep 2009
Total Posts : 5005
   Posted 12/19/2011 9:44 AM (GMT -6)   

 

       Laura...could you please explain that....I have a bottle of it from GNC?

 Maybe I misunderstood you...only one brand name company makes it? rolleyes  

   SE


Moderator Chronic Pain Forum

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Sherrine
Forum Moderator


Date Joined Apr 2005
Total Posts : 17895
   Posted 12/19/2011 10:13 AM (GMT -6)   
I saw this post and thought I could help some of you. 
 
Screaming Eagle, there is only one product called Curamin.  What is confusing is some are buying curcumin.  It's so similar in name that it can be confusing.  Curcumin is basically tumeric (curry) but Curamin has curcumin and three other things in it that all work together.  Plus, curcumin (tumeric) is difficult for the body to absorb.  Curamin has a special process that it goes through to make it far more absorbable.
 
Everyone, here is the link to the thread I started in the fibro forum.   It is an introductory link and I was telling members about this product and how it has helped me.  So far, I'm the only one taking it but I hope members will discuss this with their doctors and see if it will help them too.  Curamin helps reduce inflammation caused by enzymes in the body and this, in turn, helps with pain.  It works very much like NSAID's without the side effects.  People with various forms of arthritis are helped with this, too.  Also, do your own research and always ask your doctor before starting anything.  You don't want anything to interact with the meds you are taking.
 
 
I hope this can help some of you.  It's helped me.
 
Sherrine 
Forum Moderator/Fibromyalgia

Fibromyalgia, Crohn's Disease, Ostomy, Autoimmune Inner Ear Disease, Diabetes, Osteoporosis, Glaucoma, Scoliosis
************************
God does not give us a spirit of fear, but of power and of love and of a sound mind. 2 Timothy 1:7

Post Edited (Sherrine) : 12/19/2011 11:47:45 AM (GMT-7)


Screaming Eagle
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Date Joined Sep 2009
Total Posts : 5005
   Posted 12/19/2011 10:48 AM (GMT -6)   
 
      Thank You Sherrine! I,... and the members appreciate this information greatly. I tend to not listen well at times...and do get mixed up. Thanks for clarifying this for us! wink wink wink
 
    Now I know what to look for...when looking for it. I wanted to remind the members again...it would be best to discuss this with your Dr first before trying.
 
       SE wink
        
Moderator Chronic Pain Forum

Weekly Quote!

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Sue123
Regular Member


Date Joined Nov 2011
Total Posts : 52
   Posted 12/19/2011 12:05 PM (GMT -6)   

 

           This is not a place that we accept disrespect to either members and or Moderators! I saw nothing on Sherrines post that that suggest that her post was better! I asked her to comment here on this forum...she is well respected by the members here and on the fibro forum.

       Please review our forum rules and follow them! If you cannot do that then you need to find another forum! I personally do not appreciate it...nor do the members of this forum...nor does the Admin!!!

      If you dissagree with a Moderator...then email them!!!....or take it up with the Admin!!

       SE!!!

Post Edited By Moderator (Screaming Eagle) : 12/19/2011 10:39:29 AM (GMT-7)


Screaming Eagle
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Date Joined Sep 2009
Total Posts : 5005
   Posted 12/19/2011 12:25 PM (GMT -6)   
 
   There is enough information on the topic for our members...so thread is locked!!!!
 
   SE
Moderator Chronic Pain Forum

Weekly Quote!

"I hope to be the kind of person my dog thinks I am" author unknown
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