CRAZY SIDE EFFECTS

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Jenna Burns
New Member


Date Joined Jan 2012
Total Posts : 6
   Posted 1/27/2012 7:02 AM (GMT -6)   
I have started having a symptom that even my dr can't sat he has heard of -
I am having trouble urinating....and my vision is very blurry......
Has anyone ever had these problems, or at least has heard about it and on what meds did it happen with. Mine started with the Suboxone so I switched back to Narco and it actually has gotten worse......
 
Jenna idea

cogito
Veteran Member


Date Joined Oct 2010
Total Posts : 926
   Posted 1/27/2012 9:57 AM (GMT -6)   
The urination issue looks fairly common try googling suboxone and urination.
My guess is that it is due to a change in vasopressin levels. Suboxone is an antagonist to the K-opioid receptor which in turn will reduce vasopressin levels (an antidiuretic hormone):
http://en.wikipedia.org/wiki/Kappa_opioid_receptor
http://en.wikipedia.org/wiki/Antidiuretic_hormone

As for blurriness, a google search indicates that it too is a side effect. But I don't know the mechanism.
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