diarrhea, stomach contents, expulsion of meds

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Veteran Member

Date Joined Oct 2010
Total Posts : 932
   Posted 3/14/2012 6:51 PM (GMT -6)   
Hi all,

I have a slightly gross question. I tried googling the answer and couldn't find it. I also just called the nurse-line with my insurance and the RN didn't know either.

So maybe someone here who has had the same experience might know.

I took my daily Ultram ER around 10am. I then had a late lunch, around 2pm.

After lunch, maybe 2:15, I took some hydrocodone. But then at about 2:30, I had just a massive amount of diarrhea. The diarrhea was probably due to my lunch, a burger -- fatty food has done this to me in the past.

So, I'm wondering, if the burger irritated my stomach, and my body decided to purge it, wouldn't both the Ultram ER and the hydrocodone I just took go with it?

I got no relief from the hydrocodone, so this also leads me to presume that the diarrhea expelled not just what was in the large intestine, but all the way through to my stomach.

C4-T4 Scoliosis (disk degeneration, stenosis, narrowed neuroforamen, bone spurs), RT hip and SI joint damage from car accident. Also, pectus excavatum, supraventricular tacycardia and mitral valve prolapse syndrome.
Current meds: Ultram ER 300mg daily, breakthrough - hydrocodone 10-15mg, or oxycodone 5-7.5mg. .25-.5mg ativan as needed for sleep, Verapamil 240mg SR (for tachycardia). [/gray

Veteran Member

Date Joined Jan 2010
Total Posts : 3557
   Posted 3/14/2012 8:05 PM (GMT -6)   
I'm sorry you aren't feeling well.

It takes most people close to 20 hours to fully digest and push out your food.

If someone is not getting enough fiber or water...it can take up to 100 hours!

I don't think the Hydrocodone would make it into your intestines that quickly.
And usually, the immediate release medicines are full effect within 45 minutes.

Since the Ultram ER is meant to be a 24 hour medicine...some of it is released by the gastric juices in your stomach....but then the rest is through the enzymes in your intestine.

It depends on how much diarrhea you actually had as it most likely did not clear you entirely out. This would be where you would keep going literally a few times every hour...for a day or so. It just "seems" like more when it's diahrrea.

Your burger wouldn't even have digested that quickly in the 15 minutes to a half hour.....

If you had thrown up....that would have been the burger's fault causing gastric distress.

So, most likely....the diarrhea was caused by something else that had already digested in the intestines.

Again....this is all just basic knowledge stuff that I have learned when I got a terrible stomach virus that lasted a week...And I take a bunch of different medication from ER to IR meds as well.

But I am certainly not a Dr.!

I would contact your Dr. who prescribes these meds and ask them what to do about your medication and how to take it if you are still feeling sick....Or if you are able to hold down the burger and are hungry for dinner tonight....than it seems you got rid of the potential bug...

Good luck!
SB and "the pup who snores loudly" 
ACDF C5-C7, (no hardware), with autograft bone Nov. 2001
(reabsorption of bone 2 years later...still lost in body..expect to burp it out at anytime..haha")) 
ACDF with hardware, allograft bone Nov. 2005 
Anterior and Posterior CDF, allograft bone with BMP, removal of old hardware, use of titanium plates, rods, screws, & kitchen sink (lol) Oct 2006

Veteran Member

Date Joined Mar 2005
Total Posts : 1289
   Posted 4/1/2012 11:23 PM (GMT -6)   
you should be ok...now if you have something wlse going on like me with crohn's disease that affects the absorbtion of food, vitamins, medicianes etc...then meds might not be fully absorbed...for example i have to take ir pain meds...can't take oxycontin etc. since the meds i would be getting throughout the day would be wasted...but from 1 bout of d it shouldn't make a difference.
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