You mean MS Contin and Hydromorphone? And Opioid tolerance has no relation to topical/subcu. anesthetics....although long term Opioid use can cause hyperalgesia (aka INCREASED pain) but hyperalgesia usually doesn't occur unless the dose of the opioid is stopped or reduced (similar to withdrawal). Some people don't respond to novocaine, procaine or lidocaine....wouldn't expect anyone but a clinical pharmacologist to know this since most docs other than PM docs don't look past the pharmaceutical label...drugs like Adderall and other amphetamines can render it less effective too and some people's bodies just don't respond. I know my dentist either has to load me up on the stuff or not at all. I usually don't need an anesthetic at the dentist though.
I'm not a doctor but I do have personal experience with all of the above. Seeing another dentist is advisable if your uncomfortable though. There are some dentists who will do twilight or even full sedation with a CRNA for even minor procedures, my friends dad is an oral surgeon and does everyones teeth haha.
C6 Herniation/Buldge (my docs debate), gen. nerve pain, ankylosing spondylitis, Crohns disease, Anxiety, Aspergers, and Mild Insomnia.
-Adderall 10mg am, Oxycodone 5-7.5mg 3-4x day,Lyrica 50mg 3x day, Klonopin 1mg night, Zoloft 200mg night. It could be worse :)