Glad I could be of some help Hibee.
It really comes down to what works for the individual. I'm enthusiastic about
Nucynta because for me personally, it seems to have the least consequences, tolerable side effects (except at break through dosing), and works better than the C-IIIs in treating pain. It doesn't carry the tolerance building risks and has a lower risk for abuse than the other C-IIs (originally, it was supposed to be a C-III due to clinical trails showing limited abuse; but because its not mixed with asprin and has a suposed "likability" factor similiar to hydromorphone, its was required to be released as a C-II).
The downside is of course its newer and though it appears safer than some narcotics, synthetics are still a relatively new area in pain management, so we don't really know what the long term affects are.
One note about
tramadol specifically. Tramadol has a long half life, roughly 6 hours. By comparison, Nucynta has about
4 hours half life and oxycodone has 3.5. Therefore, with tramadol, it tends to work better on repeated doses since its metabolites "linger". Its theraputic but no doubt, but you have to becareful to have that occasional window to allow tramadol to be cleared from the body so that toxicity doesn't build up. Although only a fraction of tramadol turns into the m1 metabolite, said metabolite has a half life of 9 hours.
Just my humble opinion. Best to ofcourse discuss this with your doctor and PMD :)
MRI revealed disc bulge and test injections revealed RA. Radio Freq procedures helped for months, but pain is up and im having the procedure done again. Currently on 75 mgs of Nucynta (tapentadol - A MOR + NRI) 2 to 3 time per day and Soma 350 as needed.
Post Edited (grainofsalt) : 6/14/2012 4:42:02 PM (GMT-6)