I used to be a regular here, but got irritated with someone and stopped posting.
Anyhow, I'm back because I want to share some great news, something that has made a huge difference for me.
I've tried dozens of supplements over the years and other than short-lived placebo effects, nothing helped...till this.
about 2.5 months ago, I started taking 250mg of agmatine 2x daily. Maybe it helped a bit. Then, a few weeks later, I added 25mg of tianeptine sulphate 2x daily.
Immediately, I was doing better and now, I'm doing great!
I was taking 300mg Tramadol ER, 10mg hydrocodone 2x daily (daytime)& 7.5mg oxycodone 2x daily(nighttime).
I'm still taking the Tramadol, but rarely take anything else. I'll still wake up with some pain, and have pain late afternoon, but rather than being in constant pain, just a couple breakthrough episodes, 0 or near 0 pain otherwise.
I had zero withdrawal too... though fear that won't be so with the Tramadol.
Last month, I had my PM cut my oxycodone script back. This month, I won't need anything but the Tramadol.
I have no clue if it is the combo or primarily the Tianeptine, but don't want to experiment yet. The two (morning, dinner) have been amazing. The only side effect was some constipation, which went away after about a week.
You can Google both supplements & discuss with your PM.
Lastly, check out Proglumide to roll back tolerance and help with withdrawal. I didn't need it, but had it on my list as a backup.