Alternative to Benzodiazepines: Thienotriazolodiazepines

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cogito
Veteran Member


Date Joined Oct 2010
Total Posts : 932
   Posted 2/27/2018 2:08 AM (GMT -6)   
Ever since the FDA put a black box warning on mixing opioids and Benzodiazepines, my PM has required patients on the former to stop using the latter.

He looked the other way in my case, as my opioid doses are small, but he still indicated that he would prefer I find an alternative sleep med.

After trying Ambien, Sonata, etc. and finding them either ineffective or causing troublesome side effects, I began exploring supplements... melatonin, etc.

Eventually, I found a good anxiolytic known as phenibut... but it works on the Gaba B receptor, like some muscle relaxants. The feeling was icky, for lack of a better term.

Then, I discovered Thienotriazolodiazepines. There are quite a few in that class, available without prescription.

I discussed with my PM and he was fine with it, even though it has the same MOA as benzodiazepines. Based on my research, they can test false positive with immunoassay urine tests, but he uses rplc tests.

The challenge then was to find an reputable online vendor. The first had pills, but their doses were 4x more than I would need. Powder wasn't an option since I can't measure micrograms.

I then bought a solution, the ingredient dissolved in it at 4mg/ml. So I bought a variable micropipette, set it to 125ul and created capsules (filled cap with 100mg corn starch to absorb solution, capped, shook).

So, now, I have a 30ml bottle of the stuff equal to 120mg or 240 doses. about 10cents per dose.. not including caps, corn starch or pipette ($26)... 30ml should last me a couple years.

If only I can crack my morning pain (almost) and end of work pain (doubtful)... still searching... but I'm sick of the bullcrap with PMs, filling opioid scripts, etc..

Chartreux
Veteran Member


Date Joined Aug 2006
Total Posts : 9664
   Posted 3/14/2018 3:01 PM (GMT -6)   
With the Feds going after pain meds, I think what you did is awesome. Especially with your doctors approval!
It might come down to MM or nothing in the near future and I wonder if all this crack down on drugs is what is leading the way for more and more states to approve MM...If Texas goes MM for more medical conditions, then I think I would be the first one to get a certification.
However, I would ask this of those cracking down on drugs, what if you had a love one that needed a major operation, would you want them in surgical pain? More surgeries are being put off because of the surgical pain...that double edge sword ...
With you on this...
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* So many dx's I could write a book* "It would be nice if we could use the edit button in real life"...
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cogito
Veteran Member


Date Joined Oct 2010
Total Posts : 932
   Posted 3/18/2018 3:55 PM (GMT -6)   
Thanks Chartreux,

I'm going to post an update over a few things in another thread.
C4-T4 Scoliosis (disk degeneration, stenosis, narrowed neuroforamen, bone spurs), RT hip and SI joint damage from car accident in 2004. Also, supraventricular tacycardia and mitral valve prolapse.
Time Release: Tramadol ER 300mg. Verapamil 240mg SR (for tachycardia).
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