I voiced some concern over the long term use of apap and liver damage, he switched me over to Oxycodone-IR or I think it's also called Roxicodone. It's still 5mg of oxycodone, but nothing else. I have found that it still works but not as good as the percocet so when my back is really bad I will take a nsaid with it. The only problem I can foresee is that doctors often see this concern as an possible indication that the person is abusing the prescription. If you and your doc have a good relationship he will understand your concern and work with you. good luck.