Prednisone and Joint Pain

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Regular Member

Date Joined Sep 2007
Total Posts : 29
   Posted 1/3/2008 6:56 AM (GMT -7)   

I was on 40mg a day of Prednisone for four months. I have tapered completely off and have been off for about three weeks. Has anyone had a similar course and experienced severe joint pain in ALL joints and how long did this last? I did not have this before I started the prednisone. It hurts to walk, or do most anything. I can hardly open jars or do normal things. I feel weak and the only time I don't have pain is when I'm lying prone.


- Darren

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 1/3/2008 8:15 AM (GMT -7)   
It takes a while for the Pred to get out of your system. Everytime I reduced my dose I got horrible joint pain and even got it when I was off. It should be getting better soon. If it doesn't I would suggest a referral to a Rheumatologist. Many of us suffer with Crohns related arthritis issues. Feel better!
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

Veteran Member

Date Joined Sep 2006
Total Posts : 2527
   Posted 1/3/2008 9:03 AM (GMT -7)   
I have a great deal of joint pain associated with my CD.  I also notice severe joint pain the 1st or 2nd day I am on pred.  I also had joint pain approx 1 week after getting a Remicade infusion which would be so severe I was actually unable to sleep.  Before mid 06 I had more issues thru the years with my joints rather than my gut.
Hope the pain gets better soon
Dx with Crohn's 1987, symptoms as early as 1984.
Temp iliostomy February 2007, reversed June 2007, Ovarian cysts, migraines, allergies (incl food allergies) , oral allergy syndrome (diff than true food allergies), Asthma, Gall Bladder removed 1999, Inguenal hernia 1987

Regular Member

Date Joined Sep 2007
Total Posts : 39
   Posted 1/3/2008 3:19 PM (GMT -7)   
I thought that one of the good side effects from my being on prednisone for a short time was that the joint pain in my knees and lower back went away while I was on it. Having been off of it for almost a year now, the pain in my knees is back in varying degrees of discomfort. My doc says X-ray show tendinitis and said to use ice and take some ibuprofin(which I reminded him I am not suppose to take). For whatever reason, the pain does seem worse than it was before I started on prednisone in the first place.
47 years old
Dx 3/07 Moderate Crohn's in terminal ileum-Probably had it for years earlier
Rx Prednisone initially for 8 weeks-40mg/day then tapered down to 0
    Currently on Pentasa-2000mg/day

Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 1/3/2008 6:02 PM (GMT -7)   


Sorry to hear your having this pain post prednisone usuage. sad


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