Jodi, my allergies actually improved while on Remicade and Imuran. Prior to starting those 2 meds, I used to sneeze 20-30 times in a row, 10-15 times a day. Eating a meal caused it. Going outdoors, coming inside,
opening the newspaper or a magazine, etc. I broke out in rashes all the time. I was also tied to 2 different inhalers and an oral asthma med because the sneezing episodes signaled a wheezing episode.
My GI predicted that my asthma/allergies would greatly improve while on Remicade. He was so right. In fact they have done clinical trials on the anti-TNFs for asthma.
All that said, there are different causes of allergic responses. So you might be responding to an allergen that Remicade does not help with it does for me. I was just this morning reading an article about
it, pertaining to sudden swelling of the tongue and lips. The five groups are: Immunoglobulin E (IgE); Bradykinin-mediated group; Complement-mediated group; Nonimmunologic group; and Idiopathic. Now to what the groups mean.
From eMedicine Case Study:Immunoglobulin E (IgE)–dependent group, which may involve specific antigens (eg, foods, drugs, pollens, venoms), physical stimulation (eg, cold, vibration, exercise), or certain autoimmune disorders (eg, lupus erythematosus, cryoglobulinemia, juvenile rheumatoid arthritis, autoimmune thyroid disease)
Bradykinin-mediated group, which may involve hereditary or acquired C1 esterase inhibitor (C1INH) deficiency or malfunction or may involve angiotensin-converting enzyme (ACE) inhibitors
Complement-mediated group, in which patients may have serum sickness, necrotizing vasculitis, or a reaction to a transfusion of blood products
Nonimmunologic group, in which the disease is related to direct mast-cell activators (eg, opiates, antibiotics, radiologic contrast material) or agents that alter arachidonic acid metabolism (eg, nonsteroidal anti-inflammatory drugs, azo dyes, benzoates)
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