I am on Humira 40mg weekly and Imuran 75-100mg alternating days. I have to alternate the dosage on Imuran because I am one of the few with rare genetics that only allow me to take this dosage. My CD is moderate to severe. I was dx'd in Jan. 06 & have had one resection. I've been on the Imuran from my dx.
Tried Remecaid...built antibodies....hence the Humira. I work in the medical field and am exposed to all kinds of infection every single day. I also have not been able to come completely off predinose for the past 2 years (probably due to the lower than standard dosage of Imuran). I am tested periodically for toxity about every 4 months for the Imuran, never have had a problem. The only side effect for me has been some mild migraines so I started taking it at night so I'd sleep through them. It takes about 4 months for the Imuran to really work well. The Humira I find a whole lot easier than Remecaid and have not had any side effects other than the normal flu effects time to time. The flu effects have been a whole lot less than the Remecaid was too. There is some consideration to weigh the risks of doing both drugs together (cancer). However, in my case this has been the only drug combo that has worked for me so far. So long as I reduce my fat intake to half the RDA, stay away from sugar and trigger foods I do pretty well. I have one bowel movement a day and more often than not it's formed. Again, I stress not eating trigger foods! Is my CD under control, no...I don't think so until I'm able to come off the pred. I've had two infections; viral upper respiratory which I chose not to take anything to loosen the phelm ergo upsetting the balance of mucus protecting my stomach. I went with a neb treatment and albuterol inhaler to help with the cough and congestion. Did it take longer to get rid of, yes, but it was a nasty virus that gave several people pneumonia, however, not me because I was attentive to the problem from the onset and did not wait to get treated. The next infection was fungal and I am still dealing with it mainly because my derm misdiagnosed it as psorasis! I am currently on anti-fungal oral meds and while it is taking longer to clear up, it was very aggressive before it was properly dx'd and fungal infections are notorious for being stubborn anyway! I hope this long post will help you in your decision. It's not an easy one...but for me it's working pretty good right now.
Dx'd Jan'06, 1st Resection 7/06, Predinsone, Humira, Imuran, B12 injections, Nexium. Secondary conditions: Psorasis, Acne, Fatigue, Joint Pain, Lactose Intolerant, gallstones, fibroid cysts, peri-menopausal.