This is terribly sad how your brother is responding to this disease. After having CD for nearly 41 years I know it is a roller coaster ride, not only with the disease, but with the emotions. Not having success with medications only makes it worse. The problem with how he's handling it is more detrimental to him than anyone else because he's going to wound up aillientating himself from the support system he's going to need most. He should probably seek help from a professional. Actually, some of the meds they give for depression can help this danged disease. Anxiety of what is going to happen to us can play a big role in how the disease goes. Mine was that of fear. When was this disease going to get me good? Once I found the meds they gave me for anxiety helped my disease, I realized I could use mind over matter to help me and it worked for about 30 years. In my mind I told the CD that if it was going to get me it was going to have a hard fight because I was going to fight it with all my might. I had two children and I lived my life about as normal as others with the exception of pottying more. For that, I told myself that was "my normal" and kept on truckin ahead. It will be hard for you to suggest this to your brother, but perhaps you can talk with other family members, best with them together, explaining his attitude is only hurting him. Negativity is the worst thing for this disease, it is best fought with a positive attitude.
CD for 41 years
2 Bowel resection surgeries 2000 & 2003
Meds - None, allergic to 5 ASA and Immuran, refusing Remicade treatments and any other immune system destroying meds. Only take Loperamide to control # of BMs and so I can get out of the house. 60 years old, widowed, and on S/S disability. Amputee as a result of allergic reaction to medication Heparin given me my last surgery. "I'm going to live, live, live til I die."