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Regular Member

Date Joined Sep 2005
Total Posts : 89
   Posted 2/10/2008 10:09 PM (GMT -7)   
I was thinking about having a half grapefruit for lunch.  I haven't had any for months.
Has anybody indulged a little with no ill effects?

Veteran Member

Date Joined Mar 2006
Total Posts : 1034
   Posted 2/10/2008 10:39 PM (GMT -7)   
if memory serves, grape fruit is an odd fruit where it messes up your meds - it can cause too much to be absorbed or too little. i think entocort comes with a label saying do not eat grape fruit when on this medication. lucky for me i am not a fan of that fruit so i never ate it while i was taking entocort (or any of my meds for that matter). if you want to eat grape fruit, i suggest speaking to your doc or pharmacist about it first.
Crazy Harry

Crohn's since 1993 (17 yrs old then)
surgery in July '05 - removal of 2 inches at ileum and 8 inches of sigmoid colon (had fistula into bladder)
Nov '05 developed colonic inertia; July '06 told i needed ostomy surgery
began maker's diet in August '06 - now feeling the best ever with no symptoms of colonic inertia and i kept my colon
med free as of 10/31/07

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 2/11/2008 3:07 AM (GMT -7)   
I know that grapefruit is certainly a no-no with certain types of chemotherapy.
Co-Moderator Crohn's Forum.

Regular Member

Date Joined Nov 2006
Total Posts : 304
   Posted 2/11/2008 8:36 AM (GMT -7)   
i am on entocort and was told no grapefriut or anything with grapefruit juice now i have to read even more lables when grocery shopping...aaarrggg lol
I'm cute. Let's put me in charge.(happy bunny)
 anemia, b12 deficiancy, and malobsorption, moderate joint pain,severe weight loss, gastritis
 omega 3, digestive enzyme, calcium, vit d, flax oil, aloe vera juice, 9mg of entecort, 100mg Imuran
 diagnosed with a CT scan september of 2007.

Regular Member

Date Joined Dec 2007
Total Posts : 298
   Posted 2/11/2008 9:07 AM (GMT -7)   
Grapefruit can slow down the activity of the liver enzymes that metabolize drugs into their inactive form (Entocort, Lipitor, and many others). That leads to too much of the active drug in your system, and you can develop more severe side-effects and/or even fatally overdose. If you're on Entocort...Maybe a little bit won't hurt you...not worth the risk...eat an orange instead? :)


Post Edited (Illini) : 2/11/2008 9:15:14 AM (GMT-7)

Regular Member

Date Joined Dec 2007
Total Posts : 47
   Posted 2/11/2008 6:06 PM (GMT -7)   
uh oh, now i'm worried...i have a whole grapefruit for breakfast 3 times a week (for the last 3 weeks since I started the makers diet)....I'm currently on Prednisonse...any bad effects there?

oh and also, I haven't noticed any ill effects...in fact I've been feeling great
-Male, age 31
-Diagnosed with Crohn's 2002 - 5 surgeries for peri-rectal abscess in 2002-2003
-Started Makers Diet 26 Jan 08
-currently on prednisone taper after landing myself in the ER with a partial obstruction

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