There's just no way to say with certainty -- each case is different. There seems to be a subset of Crohns patients -- I have seen it estimated at 20% ro so -- who have fairly stable, unchanging disease throughout their lives. I seem to fit that mold, first symtoms at 19, diagnosed in 30s, 60 now and no real progression. Then there are others who have progressive complications related to fistulas, obstructions, etc. who require periodic surgeries. Overall it seems that if you have obstructive or fistulizing disease it's going to get worse -- or at least bounce from crisis to crisis -- whereas if you don't you may wind up having fairly constant non-progressive symptoms from now on.