I had a similar experience with Remicade. It slowly lost effectiveness (though I never made it the entire 8 weeks) to theI point I was infusing every 4 weeks. Insurance wouldn't cover it so I tried Humira. When that didn't work I tried Remicade again but had an allergic reaction on my second infusion. If it's still helping but just not lasting, talk to your doc about having the infusions more often. Have you tried anything like AZA (Imuran), 6-MP or methotrexate along with the Remicade? Something that helps.
Best of wishes! I know how scary it feels to think about losing Remicade!
--39 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05
--1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone
--tried Prochymal in Phase III study (can't wait til it's approved!)
--waiting to start Tysabri
--single mom to 10-year-old girl