It is known that if you go too long between Remicade infusions (more than 16 weeks, according to Centocor) you are more likely to build the antibodies to Remicade. Once you have the antibodies, you've lost Remicade. According to my doctor, some people stop responding entirely to TNF-alpha blockers. so, it seems risky to me to mess with the regular maintenance dose of Remicade. That's just my thoughts...
--39 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-year-old girl