Humira welts on injection site?

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Veteran Member

Date Joined Apr 2006
Total Posts : 733
   Posted 4/5/2008 8:24 AM (GMT -7)   
Hi, has anyone else had a rash on the injection site afterwards?  I am surprised it is still very itchy and sore now two days later, especially on my stomach. :(
Diagnosed with Left-sided UC in 1995 at age 15, Prednisone, Rowasa & Hydrocort. Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Aloe Juice, Canasa, Enotcort, Colazol, Anamantle, Remicade, etc... had 1 inch deep rectal ulcer 2004, put on Remicade, August 2007:Increased Remicade dosage-700mg every 6 weeks,diagnosed w/ Psoriatic Arthritis & Fibromyalgia Current meds: Clorazepate, Lomotil,  Tylenol pm, Lyrica started 1/17/08, Flagyl 750 mgs started 4/2/08, Humira started 4/4/08

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 4/5/2008 9:11 AM (GMT -7)   
I don't use Humira, but I have heard many who do ice the area first. They also let the Humira get to room tempature first. Hope that helps a little.
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

Regular Member

Date Joined Oct 2007
Total Posts : 289
   Posted 4/5/2008 9:12 AM (GMT -7)   
Hi,oh absolutely!!! Benedryl does help.I get that just about everytime. I'm not sure about the stomach,I use my leg,the site isn't sure for me ,but gets the itchey welt.I know others here use there stomach.

Regular Member

Date Joined Aug 2003
Total Posts : 303
   Posted 4/5/2008 9:22 AM (GMT -7)   
Yep - it happens to me too. I actually find it's better on my stomach than on my leg though. My doctor told me to try Benedryl cream and that seems to help a lot. I put it on as soon as I do the injection. Try not to scratch it (hard, I know) because that seems to make the itchiness go on longer for me. I've also found that putting a very cold washcloth on it helps.
I hope that other than that, you get some good results from the Humira!
Dx in early 1999
Resection in June 2006
Currently on Humira

Regular Member

Date Joined Jan 2006
Total Posts : 355
   Posted 4/5/2008 9:57 AM (GMT -7)   
Yes, it is a totally normal reaction.  Take oral Benadryl as needed and I would also apply the Benadryl cream or Cortaid cream on it too.  Some injections cause more of a reaction than others and I don't know why.  Thigh ones always cause a big itchy rash.  But this last tummy one did too.  Good luck.

Veteran Member

Date Joined Feb 2007
Total Posts : 734
   Posted 4/5/2008 11:24 AM (GMT -7)   
Nanners, I wished I would have read this earlier. My husband gave me my first four injections earlier today and they hurt. Ice would have helped and room temperature too. I will try that next time. I am icing now and it feels better. Your always full of good information. Thanks, Janice
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