on Remicade with positiv TB skin test?

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Regular Member

Date Joined Sep 2006
Total Posts : 21
   Posted 5/7/2008 9:14 AM (GMT -7)   
Is anyone on Remicade with postive skin test for TB?  I heard you can get an antibody test to see if you can go on Remicade..

Post Edited (danbaek) : 5/8/2008 10:43:59 PM (GMT-6)

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 5/8/2008 2:47 AM (GMT -7)   
Here's a bump for you, Dan. I hope you get some answers soon.
Co-Moderator Crohn's Forum.

Veteran Member

Date Joined Oct 2004
Total Posts : 3042
   Posted 5/8/2008 3:51 AM (GMT -7)   
Hi Dan, i have been on remicade for almost 5 years and I now no-side effects from the drug. You do get TB tested once a year.
Hi, I am teddybearweiser, I am a male.
I was diagnosed with crohns disease when i was admitted to the hospital

in 1992, in Jan of 1993 I was back in the hospital for surgery for my crohns. I had part of my right colon resectioned with ilecolonstomy.

My GI doctor has me on Asacol, Dicyclomine,Imuran,Celebrex and Remicade. B-12 injection once a month.
Also diagnosed with Osteoarthritis and Rheumatoid Arthritis

Veteran Member

Date Joined Feb 2006
Total Posts : 842
   Posted 5/8/2008 6:36 AM (GMT -7)   
I was on Remicade for some time, and I didn't have a positive TB test. But, my GI did inform me that if the TB test came back positive, it would be because of latent TB, and I could still get Remicade, but would have to be treated for the TB first.
Crohn's Disease for two years and counting (diagnosed March 8th, 2006)
Imuran: no more! Got the GI's okay to stop taking it :)
Humira: finally got approval on 9/21, done with loading doses, starting biweekly schedule on 10/10
Dicyclomine and hyoscamine for intestinal cramping and spasms

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 5/8/2008 9:21 AM (GMT -7)   
Gosh, I could have sworn I replied yesterday but I guess I never hit submit! Here it goes again!

I had a positive PPD back in 1990. Back then (way before Crohn's dx or symptoms) it was explained to me that I had been exposed to the TB virus and was carrying it around (latent) and it could activate at any time. I was given the choice to either watch it and treat if it ever activated or treat as a precaution. I chose the latter and took Izoniazid (INH) for a year. Once a PPD is positive, it will always be positive. So now I just get chest x-rays. I've been on whatever immune suppressing drug (Remicade, Humira and now Tysabri) and never had a problem.

I recommend you see a pulmonary specialist to treat the latent TB. I am not sure you will be able to take Remicade without treatment of the TB.

Also, a word of warning that I was not given... do not allow another skin test! If you were positive the first time, it will be positive again. Each time it gets worse. It is an allergic reaction and like all allergic reactions they get worse with each exposure. I didn't know that and allowed the person to retest. My bump was as big as a golf ball the second time around! I've had clinical trial people try to get me to do a PPD and I refuse.

Good luck!
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--stuck on methylprednisolone, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-year-old girl

Regular Member

Date Joined Sep 2006
Total Posts : 21
   Posted 5/8/2008 9:32 PM (GMT -7)   
Thank you guys.  I am trying to setup a consultation with the doctor who invented Remicade in Ceders to see if I'm a candidate. According to my GI doctor, he's a good friend of his.  eyes   Well I hope this would stop the bleeding I've been having for good 8 months.  This forum is very informative and helpful.  I wouldn't have imagined about hookwarm(been reading other posts) :-) if it wasn't for this site.  lol

Veteran Member

Date Joined Mar 2005
Total Posts : 2486
   Posted 5/8/2008 10:25 PM (GMT -7)   
I also had a positive PPD after returning home from Africa in 2000 and started working for the CDC. They almost pooped their pants when my screening test came back so blazingly positive. I went the INH route like sr5599; went in every month to the health department to get blood tests to check my liver function, then finished the course after 9 months. I have to get a chest x-ray every year or so, but that's it. Have you talked to your doctors about doing the INH treatment?
Co-moderator - IBS Forum

Please always remember to consult your medical professional regarding your medical questions; this forum is intended to provide patient-to-patient support. Although some of us have healthcare backgrounds, we cannot diagnose or treat patients on the board.

Regular Member

Date Joined Sep 2006
Total Posts : 21
   Posted 5/9/2008 12:03 AM (GMT -7)   
I believe my GI doc. mentioned about that. The thing is I work at a hospital as Rad. Tech. & I would eventually come across someone with TB. My fear is if I get treated for TB with INH and then somehow get exposed to it again.
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