My Crohn's is in remission clinically, but I still have bad arthritis pain which requires daily pain meds (and now I have 3 ulcers) due to the Crohn's. The fatigue may be a little better than it used to be, but I still don't have the energy a healthy person would have. So, I may not have many of the symptoms they use to measure whether or not you are in remission (D, fevers, abcesses, fistulas, etc.), but I still definitely have some problems and I don't know that they will ever go away. So, I don't know if the tiredness will go away, but I sure hope that it does soon!