Humira side effects

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Regular Member

Date Joined Nov 2007
Total Posts : 50
   Posted 5/23/2008 10:21 AM (GMT -7)   
I've been on Humira since the end of January and i just got back some blood test results.  My ALT is 94, my AST is 54 and my white count is 3.5
The nurse said they are going to check me again in a month but this makes me really nervous.  I'm tired all the time and i don't understand these counts.
Any advice or opinions on the results? confused

Veteran Member

Date Joined Aug 2007
Total Posts : 884
   Posted 5/23/2008 12:15 PM (GMT -7)   
My liver enzymes have gone up and down for years.  I've tried making the connection between Remicade or Cimzia treatments or any other medication changes and the elevated tests, but could never find a concrete link.  GI said several of the meds I'm on could raise them.  Finally, we did an MRCP, ERCP and liver biopsy, all of which just showed mild dilation in the bile ducts.  Nothing they are concerned with, just going to keep watching them and repeat the tests as necessary.  My thyroid doctor did tell me the other day that she sees a lot of patients with celiac disease who have elevated liver enzymes.  Not sure what the connection is there, but maybe there is one and, if so, maybe there is a similar connection with Crohn's.  I wouldn't worry about it too much yet...see what they are in a month.  My ALT was over 300 and my AST over 200 and they still weren't that concerned yet.  It could change a lot in a my opinion, you don't need to stress about it yet.   

...rejoice in our sufferings, because we know that suffering produces perseverence; perseverence, character; and character, hope.   Romans 5:3-4

Veteran Member

Date Joined Jan 2007
Total Posts : 3200
   Posted 5/23/2008 4:19 PM (GMT -7)   
I was taken off Humira for awhile, because of increased liver enzymes, but the GI put me back on, telling me that the benefits
were outweighing the risks. So I guess they know when the risk is too high...

Too many years with CD
Two bowel resections, several obstructions.
Fibromyalgia and recently diagnosed with chronic pancreatitis

Laughter is the brush that sweeps the cobwebs from our hearts

Regular Member

Date Joined Nov 2007
Total Posts : 50
   Posted 5/27/2008 5:08 AM (GMT -7)   
Thanks for the replies guys-that helps!
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