I have taken it for off and on 5 years. I have noticed little or no side effects: mainly a moon face as like with Prednisone. I've got off it several times and found that the last 3 mg capsule was the most difficult to end, something like Prednisone.
Entocort is broadcasted as non-systemic and topical only. I understand that whatever is absorbed and passed on to the system is removed with the first pass through the liver.
I swear by it and my only complaint is about its cost, and it won't go generic for sometime.
Retired male in late 60's. Perforated Colon in 92. Diagnosed as Ulcerative Colitis in 93. Uncontrolled flareup in 97 dictated J-pouch surgery. 04 Capsule endoscopy diagnosed as Crohns not UC. Emergency surgery in 05 to remove lodged camera capsule. Biopsies positively diagnosed Crohns at that time. 12/06 Unsucessfully tried Naltrexone(LDN). 2/07 developed scleritis of the eye, tearing and detaching the retina. Treated with high doses of Prednisone. 6/07 Thought eye was healing and started taking Entocort counting on the residual (non-systemic portion) as treating the eye. Wrong. In October eye was not stabilized. 11/07 Started Remicade to try and reduce the ocular inflamation of the Scleritis since I had been requiring more and more Prednisone to keep the eye quiet. 12/07, retina tares and detaches again. Started Remicade every 4 weeks plus 20mg of Prednisone per day. Six months and seven infusions later, good eye is back to 20/14. Bad eye is 20/70. Set for cataract surgery in June 08 on bad eye. Should return to a correcable visionary level. Life looks good (literally) today.
Married with 4 grandkids.