I have had 3 setons, I think the longest one was in was about 9 months or so. The first two healed nicely on their own and were easily removed in the office without surgery. The last sucker they tightened twice, something to do with where it was located, too close to the sphinxter muscle, that was extremely unpleasant because I didn't have good enough pain killer to get me thru. I know better now. But I just lost it 2 weeks ago and had a party! jk, but it was exciting. I celebrate when I'm feeling good in a big way, so having a drain fall out ROCKS!
I soaked alot when it was uncomfortable. I caught up on a lot of reading! I bought baby wipes to keep it clean during the times I couldn't soak or when I wasn't at home. There were days when it bothered me a lot, but then days when I didn't know it was there. NOT having one was way more painful. There is an end in sight but you have to be patient and let it do its thing. Don't let it rule you, accept the bad days and move on and celebrate the good days.
I hope the Remicade helps you. I up'd my 6mp from 50 mgs daily to 75 and 100 on the weekends, seemed to do the trick. Good luck!