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New Member

Date Joined Jul 2008
Total Posts : 2
   Posted 7/6/2008 5:31 PM (GMT -7)   
Hi to you all.
Crohns for three years, been through all the drugs, at present on methotrexate, prednisone for seven weeks but still getting diarhea heaps. anyone else out there having same problem.

Veteran Member

Date Joined May 2005
Total Posts : 511
   Posted 7/6/2008 6:12 PM (GMT -7)   
Hi and welcome to HW!!!! Sorry to hear you are having problems. How long have you been on methotrexate??
I have only had 3 injections of it so far and also on prednisone. I'm told it takes a good 4-8 weeks before the
methotrexate kicks in and starts working. Hang in there!
Living with Crohn's Disease since Jan./2000 but had a few years prior
I'm a true Crohnie with IBS too
Meds I have tried:  Too many to list- LOL
Meds currently on:  Prednisone 20mg tapering
                           Methotrexate injections once a week 25mg
                           Folic Acid 5mg once a week
No Surgeries

New Member

Date Joined Jul 2008
Total Posts : 2
   Posted 7/6/2008 7:02 PM (GMT -7)   
Hi LBJ, Was diagnosed 3years ago, have crohns of the small bowel with stricture of the illium and gastritis and duodenitis. Been on 40mg Prednisone for most of that time plus all the other usual drugs. Have been having weekly 20mg Methotrexate injections in the stomach for last 7 weeks while tapering of pred ( down to 15mg at present ) plus folic acid weekly and vit D, Calcium and losec daily.Not sure how up to date we are here in New Zealand treatment wise but should be grateful as some poor sufferers have had it for many, many years, I am 60years old now, so a late starter for an old girl to aquire such a desease.

Regular Member

Date Joined Jan 2006
Total Posts : 158
   Posted 7/7/2008 7:07 AM (GMT -7)   
Welcome to HW. I'm on MTX as well. I'll do my fourth injection today. So far I haven't seen much of a difference. The frequency of pain has been a little bit less lately, but that may be due to the Flagyl and Folic Acid that I started last week. Still lots of D though.

good luck to you :)

Veteran Member

Date Joined Jul 2006
Total Posts : 6927
   Posted 7/7/2008 7:19 AM (GMT -7)   
Welcome to healingwell, MTX shot is about the only thing that has helped me I take 25 mg once a week (but I am a big person). I would think about folic acid daily if I were you. I am also wondering what you mean by heaps of diarrhea I went from about 30 a day to about 10-12 a day but it took me a couple of months to do it.
Forum Co-moderator - Crohn's Disease
We will find a way, or make one.-Hannibal (crossing the Alps in the 15th Century on war elephants) 
Make sure your suffering has meaning...-?
All suggestions/options/opinions are caveated with please consult with your local health care provider...

Post Edited (MMMNAVY) : 7/7/2008 8:24:32 AM (GMT-6)

Veteran Member

Date Joined Mar 2006
Total Posts : 1354
   Posted 7/7/2008 5:55 PM (GMT -7)   
Welcome to HW. Like the other posters have said, Methotrexate can take a few months to kick in. It took a good 4 months for me although I take it orally, be patient and I hope it will bring relief soon.

Regular Member

Date Joined Oct 2006
Total Posts : 367
   Posted 7/8/2008 5:37 PM (GMT -7)   
I haven't been on methotrexate, but i have many friends with RA that swear by it. I hope you start feeling better soon!

Veteran Member

Date Joined Feb 2007
Total Posts : 734
   Posted 7/8/2008 7:52 PM (GMT -7)   
I hated Methotrexate. Always left me feeling crummy and never really felt it helped. If you read what it used to be used for, then you can understand why it's so hard on us.

Regular Member

Date Joined Feb 2008
Total Posts : 91
   Posted 7/8/2008 9:25 PM (GMT -7)   
I take Methotrexate and have taken it can take up to 12 weeks to begin to have the full function. Also are you increasing your doasage as you go. I have taken this drug in prior years and back on it again. So it is like a been there done that. As for the prednisone just take one step at a time in regards to decreasing it.

The medications and procedures in kiwi land is as up to date as every where else. Trust I have lived in many countries (6 in total) over the years and endured treatment for Crohn's in everyone of them.

CD diagnosed 34 years ago
Stem Cell Transplant may be back on
Lap-assisted Ileocolic Resection- February 2008
Ankylosing Spondylitis
Back on Prednisone - I hate it
Ranitidine HCL 
Prednisone 1% (eye drops)
Maxidex  (eye ointment)
Homatropine 5% (eye drops)
B12, Folic Acid, Vitaman D, Calcium

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