Maintenance drug - 6MP

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Regular Member

Date Joined Jun 2006
Total Posts : 28
   Posted 7/9/2008 2:39 PM (GMT -7)   

On May 15th I had a resection to remove a stricture that I’ve been living with for 2 years and I also had an abscess removed. (I think the abscess was my major problem.) The surgeon said everything else looks good and he saw no other signs of crohn’s  when he was in there. Anyway, now my G.I. doctor wants to put me on 6MP as a maintenance drug.

Anyone in this same situation?

Anyone taking anything different?

Thanks in advance…

Veteran Member

Date Joined Sep 2007
Total Posts : 565
   Posted 7/9/2008 6:50 PM (GMT -7)   
i am currently on 6mp, possibly going to see surgeon in the next 6 months and even though i haven't been 100% successful with 6mp (possibly due to scar tissue) my gi would like to keep me on it after my resection as a maintenance med. so yes, i have heard of it :) he would like me to be on 6mp or some other med i am not familiar with ...i think it started with an M.

good luck and hope you are healing well! (no pun intended!!!)
.: stephanie :.
33 y/o female diagnosed 8/8/7 with crohn's of the terminal ileum w/ stricture/scarring
meddies: 6mp, percocet, trazodone, ativan, iron, calcium, folic acid & some other vits

ski bum
Regular Member

Date Joined Jan 2007
Total Posts : 451
   Posted 7/9/2008 7:05 PM (GMT -7)   
I had a resection in April. My GI wanted me to be on Imuran and my surgeon thought Pentasa would be adequate. To my knowledge, the studies have been equivocal as to whether any of these drugs actually prolong remission and prevent recurrence (I could be wrong about this though), so I decided to go with my surgeon's recommendation and I'm taking Pentasa, because the potential side effects and risks are less severe than Imuran's. If I have a recurrence, my GI told me he'd recommend I go back on Humira.
50 y/o F. CD dx'd Aug 05. Initially on Pentasa, then Imuran 125 mg. Started Humira (very reluctantly) on 10/24/07. Ileocolectomy 4/08.

Veteran Member

Date Joined Jan 2003
Total Posts : 734
   Posted 7/10/2008 11:25 AM (GMT -7)   
I had abcess after abcess and they would not heal - 6 surgeries later and after Remicaide I started 6 MP.  It is now my "drug of choice".  I have been on it for about 5 years now with no problems or side effects and the abcesses are long gone history.  I have bloodwork done every three months to keep a check on things and once a year for liver enzymes.  I also take Pentasa, but was on it for a couple years before the 6MP.  Together they seem to do the trick for me.

"We can't beat this disease, YET, but we can't let it beat us!"

"Do not worry about tomorrow, for tomorrow will worry about itself. Each day has enough trouble of its own." Matthew 6:34

Veteran Member

Date Joined Mar 2007
Total Posts : 1633
   Posted 7/10/2008 2:02 PM (GMT -7)   
Ski bum,

Studies are equivocal about the effectiveness of Pentasa (and other 5-ASA meds) in prolonging remission, but studies are quite clear (unequivocal) about the effectiveness of 6MP/Imuran.

Regular Member

Date Joined Nov 2004
Total Posts : 158
   Posted 7/11/2008 12:08 PM (GMT -7)   
I have been on 6mp for several months here and there (due to pregnancy and adverse effects). I love it. Even though some days I have symptoms of crohns, I never get the terrible pain like I did before starting 6mp. And I don't get the fevers, joint pain and skin inflammation. I have even been able to stop the asacol which with 4 kids under 5 was awesome. It was very stressful taking asacol 3x a day!

Hope you do awesome with it!

Diagnosed with UC in July of 2003 then diagnosed with Crohns in August of 2006.

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 7/11/2008 12:30 PM (GMT -7)   
I have had two resections myself. After the 2nd one they tried me on 6mp, but it didn't work out for me. I only take Asacol now. Its working well to keep the inflammation down for "me".

By the way SallyC, I take my Asacol twice a day. 3 caplets in the morning and 3 at night. I would forget the afternoon dose if I didn't take it like that, and my GI said twice a day was okay.
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

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