My husband was in a very similar position to yours in March and April this year. He had a very rough time being sick, and was in the hospital for over 6 weeks, and is still recovering. They also had difficultly finding veins to stick him in, though he didn't get a picc line. Instead, we had folks from the emergency room or the lab come and change his IV. They were so much more efficient and capable at finding viable veins, and when they did it, they didn't seem to have much trouble at all. His regular nurses had a lot of trouble finding veins. I've heard that picc lines can be the source of infections, and we wanted to avoid it if at all possible. And thanks to the emergency room nurses and the lab techs being so kind to us, we did avoid the picc line successfully.
My husband had both c-diff and a crohn's flare together, and the doc said his colon inflammation was the worst he'd ever seen. Even at 120mgs of solumedrol, my husband got little to no relief, and was in pain, and on dilaudid constantly. He was definitely headed towards surgery to remove about 1/2 of his colon, and come back home with a bag. Remicade was tried as a last ditch effort, and it helped him get out of the hospital. He's now on remicade every 8 weeks, and is doing much better than he was at the hospital and rebuilding his strength. He's not fully back to normal, but he is much much better.
If you haven't tried remicade yet, give it a shot, if you are don't have other concerns that preclude you from trying remicade. I was and still am very worried about side effects from remicade, but as far the crohn's is concerned, it really helped my husband avoid surgery and get out of the hospital. Also, Ensure drinks helped my husband's nutritional status (even though in the end he had lost 35 lbs, and was very weak).
I hope you start feeling better very soon.