question about kidney scarring & crohn's

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New Member

Date Joined Mar 2005
Total Posts : 15
   Posted 7/26/2008 9:44 PM (GMT -7)   
I 'm wondering if anyone has had any issues with scarring of their kidneys in addition to having Cronn's. I've been diagnosed with Crohns for over 7 years. I'm on asacol and asulfasalazine. In addition to Crohns, I have Crohns related arthritis and uveitis. The eye problems (for the last few years) have been thankfully, inactive. The arthritis though, gives me plenty to complain about!

Upon a recent visit to my new PC doc - I mentioned some symptoms of a UTI. For me, these symptoms can sometimes be confused for Crohn's issues - as my diagnosis is a mild onel My new doc send me for a cat scan. The results indicated scarring on the kidneys. So I had another cat scan, focusing on the kidneys. I'm awaiting an appointment with a specialist next month. All I know for now, is that it isn't normal inflammation. They think it could be related to my meds or something else, more serious. For the moment, I'm in limbo - waiting until mid August for my appoinent. (and I have my yearly colonoscopy a week later - my summer keeps getting better and better!)

My question to all of you is - has anyone had any kidney related issues due to meds? or Crohns related?

Many thanks in advance.

Forum Moderator

Date Joined Nov 2003
Total Posts : 7122
   Posted 7/27/2008 9:17 PM (GMT -7)   
somewhere in the neighborhood of 10-25% of people with CD have kidney issues related to their CD. Most often the kidney involvement is in the form of kidney stones. But there are other kidney issues that are seen in CD patients. They are quite rare. For example, from one of my sources I found this reference: "Hydronephrosis occurs in 3 to 6 percent of patients with Crohn's disease and may be due to ureteral obstruction as a result of intra-abdominal scarring.[9]."

There are several places online to check the side effects of medications [] and there are also places to check for interactions of medicines []. I don't believe that asacol or sulfasalazine are knwon to cause kidney problems other than discoloring the urine. However, I would closely read the side effect listings.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Veteran Member

Date Joined Mar 2007
Total Posts : 900
   Posted 7/27/2008 9:52 PM (GMT -7)   
I have been on sulfasalazine for years now and have always been told to drink a full glass of water with this med because it can cause liver and kidney problems. I suppose it depends on how high your dose is... They also recommeded it be best to eat something with it. I've had problems with kidney stones several times... and have also had urethral stritures.. which have had to be dilated. I never thought to ask if it was CD related.
Will be thinking about you and sending good thoughts and prayers your way.. please let us know how you are doing.
Love and prayers
51 yr.old retired RN,Crohn's D for last35 yrs..severe esophagitis, migraines,strictures,urethral stricture,depression,probable MS.,RLS, arthritis

New Member

Date Joined Mar 2005
Total Posts : 15
   Posted 7/29/2008 5:18 AM (GMT -7)   
thanks for the kind replies. I will try and increase my water intake. And try not to worry so much, while I wait for my August doctors appointments.
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