This study was part of the testing of Humira prior to its approval for use in CD. At that time, Remicade was the only biologic approved for usage. They were testing to see if people responded to Humira after they had been on Remicade because at that time, it was not known if the Remicade usage might change the way people responded to Humira.
Papaakis is saying that Humira is another drug choice when Remicade no longer works. Studies were also done on CD patients that had never had Remicade to test Humira's effectiveness. I believe these trials were called Classic II.
Go to Remicade's home page and read the Improtant Safety Information. Then do the same at Humira's site. You'll see the extensive list of precautions. They are quite similar.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.