Yes, it's ok to have a relationship with a V fistula. I always encourage my husband to wash after contact as I'm likely to have germs from drainage there. Also, for us, it's even more important to urinate (as gyns suggest) and to wash soon after. Basically, if you have bacteria, stool, or drainage from the fistula, you can be moving it around. Yes, it can hurt but there are some great lubricants out there. By all means, this disease takes so much from us---if you can have the relationship in a safe, healthy way and you feel strong enough to do so, I say go for it!
As for taking 6mp, I took it in the morning with my pentasa and vitamins and breakfast. Was on it for several years.
23 years with moderate Crohn's/colitis; fistulizing crohn's; pentasa, just started humira