My histology results are back

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LondonRed
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Date Joined Oct 2007
Total Posts : 1190
   Posted 8/15/2008 10:00 AM (GMT -7)   
How am I to read into this?
 

Histopathology Report – Cromwell Hospital London

 

Specimens Received:

 

Rectal Biopsy                                - Active Chronic Inflammation

Rectal Biopsy                                - Active Chronic Inflammation

Sigmoid Biopsy                              - Normal

Transverse Colonic Biopsy            - Normal

Right Side Colonic Biopsy              - Active Chronic Inflammation

Ileum small bowel Biopsy             - Normal

 

No evidence Malignancy

No Evidence of Dysplasia

No Evidence of Granuloma

 

Large Bowel Mucosa – Minimal distortion of glandular architecture.

No abbesses

Polymorphs are seen in places on the surface of the epithelium.

 

Histology Diagnosis:

“Some features here are of Chronic Active Colitis and could be consistent of IBD or an infective cause must be considered”

 

GI Diagnosis:

“Mild Crohn’s Colitis but no evidence of Granuloma - inconclusive results”

 

Medication:
Pentassa x 4g a day for 3 months then taper down. Steroids 5mg for 1, 2 or 3 months depending on need.


Diagnosis Oct 07 and then Aug 08: Patchy Ulcerative Pancolitis or Chrohn's Colitis to be confirmed after biopsy.
Medication: 4000mg Pentasa a day, 5mg Clipper Steroid (Beclometasone dipropionate) for 30 days


MikeB
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Date Joined Mar 2006
Total Posts : 1169
   Posted 8/15/2008 10:05 AM (GMT -7)   
I'm not sure what the visual report from the scope showed -- was it apparent inflammation or ulcerations in the areas flagged by the biopsies? If so I would think that this shows a pretty high likelihood of an accurate Crohns diagnosis, given the skip areas of active inflammation and intermediate healthy mucosa. The absence of granulomas is not a defining factor -- biopsies of Crohns patients sometimes show granulomas (which is pretty definitive of Crohns) and sometimes not, depending on disease activity and longevity at the time the samples are harvested.

LondonRed
Veteran Member


Date Joined Oct 2007
Total Posts : 1190
   Posted 8/15/2008 10:08 AM (GMT -7)   
It was apparent inflammation as opposed to ulcerations. This is my 2nd colonoscopy in 1 year and they have exactly the same results. No small bowel inflammation, no granuloma, and two patches of inflammation on my colon which again they say could be IBD or from an infection but never conclusive either way.

Diagnosis Oct 07 and then Aug 08: Patchy Ulcerative Pancolitis or Chrohn's Colitis to be confirmed after biopsy.
Medication: 4000mg Pentasa a day, 5mg Clipper Steroid (Beclometasone dipropionate) for 30 days

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