Imuran and bruising

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Regular Member

Date Joined Jun 2008
Total Posts : 167
   Posted 8/24/2008 1:27 PM (GMT -7)   
Has anyone had any issues while taking Imuran and bruising easily? I have never had so many bruises!
I don't wear shorts because my legs have so many.
I am wondering if I should give my dr a call or if it is just something I have to deal with.
Dx with Crohn's in 1997 after 5 years of worsening symptoms.
Resection a few months after dx after 1 month on TPN and IV steroids.
Also have severe asthma.

Tried: Pentasa, Cholestyramine

Presently taking: 3.2 grams Asacol, 150 Imuran (just started June 08), back to 10mg predisone, probiotics. For asthma I take Advair 500, singulair, arieus

Forum Moderator

Date Joined Nov 2003
Total Posts : 7120
   Posted 8/24/2008 1:43 PM (GMT -7)   
Hopefully, your prescribing doctor ordered periodic blood testing for you. Imuran can cause issues with blood cells so that is why one should have routine blood work. I suggest you call the office, make them aware of the problem, and hopefully, he/she will order some lab tests.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Dave D
Regular Member

Date Joined Aug 2005
Total Posts : 404
   Posted 8/24/2008 6:15 PM (GMT -7)   
I have had 11 infusions and have found brusing and easy bleeding as side effests.
my bloodwork is showing normal, other than anemia. Also, I am getting skin tags and moles showing up almost over night.
Dave D
Retired male in late 60's. Perforated Colon in 92. Diagnosed as Ulcerative Colitis in 93. Uncontrolled flareup in 97 dictated J-pouch surgery. 04 Capsule endoscopy diagnosed as Crohns not UC. Emergency surgery in 05 to remove lodged camera capsule. Biopsies positively diagnosed Crohns at that time. 12/06 Unsucessfully tried Naltrexone(LDN). 2/07 developed scleritis of the eye, tearing and detaching the retina. Treated with high doses of Prednisone. 6/07 Thought eye was healing and started taking Entocort counting on the residual (non-systemic portion) as treating the eye. Wrong. In October eye was not stabilized. 11/07 Started Remicade to try and reduce the ocular inflamation of the Scleritis since I had been requiring more and more Prednisone to keep the eye quiet. 12/07, retina tares and detaches again. Started Remicade every 4 weeks plus 20mg of Prednisone per day. Six months and seven infusions later, good eye is back to 20/14. Bad eye is 20/70. Had cataract surgery on June 05 on bad eye. Eye returned to a correctable visionary level of 20/40. Life looks good (literally) today.
Married with 4 grandkids.

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