Humira Pen or Syringe?

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Regular Member

Date Joined Jul 2007
Total Posts : 239
   Posted 8/26/2008 4:16 PM (GMT -7)   
Pending insurance approval I will soon be starting on Humira. But which one? Does one hurt more than the other? Or cost more? I think you might have more control with a syringe, but a pen might be easier? Anyone done both?
diagnosed w/Crohn's 11/06. 34f with 2 boys, a lovable dog, and a wonderful husband. 150 mg Imuran, bentyl, vicodin as needed, metoprolol for orthostatic hypotension and heart palpitations. Bowel resection 9/07. Active disease back, darn it 8/08. 11 year old son with IBS-C, on Bentyl.

Cookie's Wife
Regular Member

Date Joined Aug 2005
Total Posts : 299
   Posted 8/26/2008 7:11 PM (GMT -7)   
I do the pen and love it. It's easy and I don't thik it hurts that bad! I leave it out for about an 1/2 hr. before the injection. Good luck!


ski bum
Regular Member

Date Joined Jan 2007
Total Posts : 451
   Posted 8/26/2008 7:18 PM (GMT -7)   
When I was on Humira, the first month starter package was only available in the pens. That way, you can see how you like the pens. I switched to the syringes after the first month and liked them better. I'm a nurse and don't have a problem giving injections. I think if I didn't have that experience, I would have stuck with the pens. I think they both hurt about the same (some burning discomfort when injecting). The pens are really easy, just a lot of parts to throw away. Good luck! You'll be OK either way.
50 y/o F. CD dx'd Aug 05. Initially on Pentasa, then Imuran 125 mg. Started Humira (very reluctantly) on 10/24/07. Ileocolectomy 4/08.

Regular Member

Date Joined Aug 2006
Total Posts : 331
   Posted 8/26/2008 9:39 PM (GMT -7)   
Started with pens, switched to syringe due to bad reaction site.  Like the syringe better, the pen feels like a "slicing" to me & just hated it.  However, still have the reaction at the site.  Good Luck.

Dx with CD 1987, 3 colon resections, 3 rectal abcess sx, anterior cervical neck fusion with plate & screws,6/2008. Major depression/anxiety, kidney stones & sx to remove, now 45 yrs old.  Still trying to figure out this disease & all the little extra complications that come with this rollarcoaster of a life with CD. Meds:Humira 40mg every other wk, Imuran .75 daily, welchol 625 x 3 daily, cymbalta 60 mg daily, fish oil, vit e,folic acid,Vit B12,inject monthly, Oscal w/Vit D, vicodin 4-5 daily 5/325,xanex .5 daily

Veteran Member

Date Joined Mar 2007
Total Posts : 1642
   Posted 8/27/2008 10:53 AM (GMT -7)   
I use pens and I like them. I would say do what you want. sometimes it does not hurt at all and sometimes it does. Depends on where i give the shot and how long I leave out the pen... etc


Karen (Karendee)

Diagnosed w/ Crohn’s Disease  March 2007 Started Humira June 2008 (have been on other cd meds)

Diagnosed w/  Fibromyalgia May 2007 on Soma and Lyrica

Diagnosed w/ General Anxiety Disorder in 2005- Effexor and Clonazepam 


Regular Member

Date Joined Oct 2007
Total Posts : 76
   Posted 8/27/2008 5:06 PM (GMT -7)   
I use the pens and really like them.  They're very convenient and simple to use.  I haven't used the syringes and don't plan on it, since I do like the pens so much.  I have also found though that it hurts a lot less if you let the medication warm up for a bit.  I got my pens the other day and they were soooo cold out of the shipping box, and wow, did it burn!  I think that was my worst injection, with it coming straight out of dry ice.  Good luck to you!
Crohn's Disease/Colitis (diagnosed 12/02), Diverticulitis (diagnosed 6/07)
Positive blood test for wheat allergy, (11/07); Positive capsule endocopy showing Celiac disease (6/30/08), also allergic to egg white protien.
Taking Asacol, Prednisone, Humira, NuLev, HCTZ, Lisinopril, Cymbalta, Prevacid, Zantac, Ambien, Lomotil, Soma, Plaquinil, Frova, Premarin, Entocort, Xifaxan, Creon, Ultracet, Vicodin, Questran powder/Carafate suspension, and LOTS OF VITAMINS AND SUPPLEMENTS!

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