How long before noticing results on Humira?

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New Member

Date Joined Aug 2008
Total Posts : 2
   Posted 9/9/2008 4:16 AM (GMT -7)   
Hey guys.

I've taken two injections of Humira now, and even tho I think i've noticed some minor results I still have some issues.
How long did it take for you guys to notice major results on Humira?

Regular Member

Date Joined Jan 2006
Total Posts : 355
   Posted 9/9/2008 9:17 PM (GMT -7)   

At three months, I noticed a lot of improvement.  By four months I was in my first every remission.  I remain so still, 2 1/2 years later. 

Good luck.  I hope you get good results too. 

Veteran Member

Date Joined Aug 2007
Total Posts : 884
   Posted 9/10/2008 10:51 AM (GMT -7)   
Skurten, I've been on it for over 2 months and have only noticed it helping some of the time (some injections don't seem to do anything at all).  My GI said I should know in 2 weeks but my rheumy said it should be working at it's full force by 4 months.  Good luck, I hope it works better for you than it has been for me!

Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 

Regular Member

Date Joined Jul 2008
Total Posts : 186
   Posted 9/11/2008 1:36 PM (GMT -7)   
Tomorrow will be 4 months on Humira. I've had only slight improvement. Just met with my GI and he wants me to increase from bi-monthly injections to weekly injections, so we'll see if that makes the difference.
39 years old female, Dx'd 2000 Crohn's Colitis in entire colon
Allergic to Asacol/Pentasa/6MP/Immuran and many others (too many to remember)
Past meds: Cipro, Pred
Current meds: Humira (...and waiting for it to work)

Regular Member

Date Joined Mar 2007
Total Posts : 257
   Posted 9/12/2008 12:52 PM (GMT -7)   
I have been on Humira for about a year and a half, I still only do one shot every two weeks.  I felt better after about three months on Humira but then kind of hit  plateau for a while and then felt better again after about 8 months.  Things are not perfect yet but they are sooooo much better than before.  I also found that limiting my sugar intake helped my crohn's quite a bit.  I can't seem to completely eliminate sugar from my diet but even cutting back helped.  MB

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 9/12/2008 3:54 PM (GMT -7)   
I noticed small improvements right away, but even now, six months in, I am still noticing improvements every week. All I can say is, be patient. I hope you start to see some bigger improvements soon.

btw, welcome!!

Co-Moderator Crohn's Forum.

Veteran Member

Date Joined Mar 2007
Total Posts : 1642
   Posted 9/13/2008 8:35 AM (GMT -7)   

I noticed improvements right away. I have been on 3+ months and see more improvement now than before. I am almost sure I am in remission... or at least very close.  It seems to take a while to take the full effect but I love the medicine. I feel like a different person.

good luck!



Karen (Karendee)

Diagnosed w/ Crohn’s Disease  March 2007 Started Humira June 2008 (have been on other cd meds)

Diagnosed w/  Fibromyalgia May 2007 on Soma and Lyrica

Diagnosed w/ General Anxiety Disorder in 2005- Effexor and Clonazepam 


Regular Member

Date Joined Feb 2008
Total Posts : 493
   Posted 9/14/2008 5:16 PM (GMT -7)   
Karendee--I'm so happy you are doing so well on the humira. You and I started around the same time.

Skurten--While I am definitely much stronger than I was when I started on July 1, I am now more limited in what I can eat than I was in July and my fistulas are kicking up something terrible. Seems like stools just pours out with D and out of my rv fistula. I was really hoping this drug would help my fistulas.

I am looking to give this drug until the end of October to really show me something. Here's hoping and praying!

Best of luck to you!
23 years with moderate Crohn's/colitis; fistulizing crohn's; pentasa, just started humira

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