FYI-- phenergran in an IV

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Veteran Member

Date Joined Nov 2005
Total Posts : 1340
   Posted 9/19/2008 10:18 AM (GMT -7)   
This article in the NYTimes is mostly about a lawsuit, but it pointed out something I did not know. There is a risk of gangrene when Phenergran is improperly administered in an IV push. I know I've had it administered this way before. I'll pay closer attention next time.

sorry, I forget how to activate the link.

[*I just activated the link - C2]

Post Edited By Moderator (CrohnieToo) : 9/19/2008 9:45:14 PM (GMT-6)

Regular Member

Date Joined Nov 2003
Total Posts : 437
   Posted 9/19/2008 10:21 AM (GMT -7)   
They have had similar experiences at my local hospital, so now putting Phenegren in an IV is banned at the hospital. So, it's either IV Zofran, or IM Phenegren.

Veteran Member

Date Joined Oct 2004
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   Posted 9/19/2008 1:08 PM (GMT -7)   
Me too! Since its commonly used for bad Renal Colic ( from Kidneystones, causes nausea as well as pain..). Many times I've had it, without many problems.

Except burning & stinging in the vein.

Regular Member

Date Joined Feb 2006
Total Posts : 261
   Posted 9/19/2008 1:43 PM (GMT -7)   
phenergan should only be administered IM or as an IV piggyback.  Meaning the medication is put into an IV bag of fluid.  I'm an RN and our hospital standard is the phenergan must be mixed with at least 10ml of saline for IV push.  I never do IV push as I'm aware of the risk involved.  I always mix phenergan in a 50ml bag of saline for slow infusion.  I myself had phenergan infiltrate a vein in my arm.  Luckily my tissues did not die but my arm was very sore for a  month.
31year old female
CD of Terminal Illeum and Rectum Diagnosed 12/04
Unable/Unwilling to use immunosuppressents due to Melanoma history in 2000.
Illeocolonic Resection 1/08  (18 inches of terminal illeum, illeocecal valve, right colon and appendix)
Current Meds: Pentasa, Fosomax, Iron, Vitamin b12 injections, Vicodin, Flagyl

Regular Member

Date Joined Jan 2006
Total Posts : 449
   Posted 9/19/2008 5:15 PM (GMT -7)   
I was just in the hospital in July and was giving phernergan and dilaudid via IV and PICC, but only with a flush. I was not allowed any oral meds as I was on bowel rest and all clear liquid diet.

It's good to know this information for future stays. I will say that the combination of phenergan and dialudid TORE UP MY VEINS!!! Plus, I was on steroids. BAD COMBINATION. I blew threw 4 IVs in 24 hours and then the doc came in and ordered a PICC after the nurse was getting very frustrated and even though IVs don't bother me, she was extremely worried about damaging my veins. So, she called the doc ASAP and got the PICC ordered. I underwent a CT scan an (pretty much) emergency sigmoid colonoscopy which involved an enema and they loaded me up on pain meds beforehand, so with all the phenergan, dilaudid, and veins just kept blowing.. I had bruises for weeks!!! I still have my PICC scar!
Kaycie - Age: 26
Crohn's - Dx Nov 05
Failed Remicade, moving onto a Clinical Trial called ABT-874 - Tentative start date - 10/2/08 - 10/16/08  - Infusion, every 4 weeks.
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 13 months old

Veteran Member

Date Joined Mar 2006
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   Posted 9/19/2008 5:44 PM (GMT -7)   
I got phlebitis from having it pushed in an IV. Hurt like heck. They acted like it was a problem with my viens. Right. I ended up having an ultrasound of my arm because I was worried about blood clots. My arm was hot, swollen and painful.
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Taking Asacol, Questran, Toprol XL (for high blood pressure). Tapered off prednisone a month ago!

Veteran Member

Date Joined May 2003
Total Posts : 9448
   Posted 9/19/2008 8:42 PM (GMT -7)   
Yep, I went thru that and DID have a blood clot in the axillary vein in addition to the superficial thrombophlebitis in the lower arm.

Improperly diluted phenergan and Toradol. I shouldn't even have been given Toradol since I'd advised them I had Crohn's disease. Both were given in one injection at the first "port" above the IV set instead of in the IV bag or at least the upper port closest to the bag. How much diluent or saline or whatever was used I don't know - except that it wasn't enough!!!! I've NEVER had a problem w/IV phenergan before or since, not even a stinging.
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.

Regular Member

Date Joined Jul 2008
Total Posts : 71
   Posted 9/19/2008 11:33 PM (GMT -7)   
I had phenergren and demeral in my pic line for pain a lot when I was in the hospital. I had no idea. I never had a problem with it but I was also on TPN in the pic would that have made a difference?.
 DX'd with UC 2000.
 DX'd with CD 8-9-08
 allergic to Asacol
 Colazal made it worse
 Prednisone 20mg X2 daily   
 Flagyl 500mg X2 daily
 First Remicade infusion 8-9-08
 Toprol XL --  Hypertension
 Insulin   --   Diabetes 

Veteran Member

Date Joined Oct 2004
Total Posts : 3932
   Posted 9/20/2008 5:19 PM (GMT -7)   
Toradol I've had, I don't think ER docs consider it bad for CD. Its more like super Tylenol..


Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 9/21/2008 6:51 PM (GMT -7)   
Wow...that's for the info!
Dx'd Jan'06, 1st Resection 7/06, Humira, Imuran, B12 injections, Nexium, Lexapro, Glucosamine, Multi-Vitamin, Ultracet Secondary conditions: Psorasis, Osteoarthritis, Fibromyalgia, Lactose Intolerant, gallstones, peri-menopausal.

Veteran Member

Date Joined May 2003
Total Posts : 9448
   Posted 9/22/2008 1:24 AM (GMT -7)   
Toradol is NOT like super Tylenol. It is an NSAID. Read up on it. For those who can tolerate NSAIDS w/o problems many in the medical profession are finding it as effective for pain as morphine w/o the nauseating effects.
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.

Veteran Member

Date Joined May 2005
Total Posts : 4219
   Posted 9/22/2008 5:27 AM (GMT -7)   
Do IV NSAIDS have the same effect as swallowed pill NSAIDS? I was wondering if bypassing the gut makes them easier to handle.
26 Year old married female law student (last year!!). Diagnosed w/ CD 4 years ago, IBS for over 10 years before that, which was probably the CD. I am sort of lactose intollerant too but can handle anything cultured and do well w/ lactose pills and lactaid. For crohns I am currently on Pentasa 4 pills/4x day and hysociamine prn. I also have bad acid reflux and have been on PPI's since age 13. I have been through prilosec, prevacid, and nexium. Currently I am on Protonix in the morning and Zantac at night. I also take a birth control pill to allow some fun in my life.

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