Tendon Damage from Cipro or Levaquin anyone?

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Regular Member

Date Joined Feb 2003
Total Posts : 101
   Posted 9/20/2008 2:56 PM (GMT -7)   
Hello I'm writing this because I did a search to see if anyone has had this problem....To no avail I came up empty...
I was wondering if anyone has ruptured or damaged a tendon from the use of Cipro or Levaquin? I had surgery March 2006 of a torn tendon in my foot. I'm wondering if other Crohnies who have taken Cipro have tendon problems now.

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Date Joined May 2005
Total Posts : 4219
   Posted 9/20/2008 4:55 PM (GMT -7)   
MamaDove had this problem. She has been sick so I'm not sure how soon she will be around. My mom is in an orthopedic boot to avoid a tendon rupture. She had been on Cipro in the past for UTI's.
26 Year old married female law student (last year!!). Diagnosed w/ CD 4 years ago, IBS for over 10 years before that, which was probably the CD. I am sort of lactose intollerant too but can handle anything cultured and do well w/ lactose pills and lactaid. For crohns I am currently on Pentasa 4 pills/4x day and hysociamine prn. I also have bad acid reflux and have been on PPI's since age 13. I have been through prilosec, prevacid, and nexium. Currently I am on Protonix in the morning and Zantac at night. I also take a birth control pill to allow some fun in my life.

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Date Joined Aug 2007
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   Posted 9/20/2008 7:37 PM (GMT -7)   
I've been on Cipro a few times and been ok, but once I was on it in combination with steroids. I was on bedrest, right after my hemmorhage... so I *know* I did nothing to injure my ankle. But, I woke one morning and was unable to walk on it. Took a month to heal. I figure I as lucky, hearing all the other stories. I am very cautious with my Cipro use now.
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--methylpred - finally off 6/15/08, tried Prochymal in Phase III study (can't wait til it's approved!)
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--single mom to 10-yr-old girl

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Date Joined Nov 2003
Total Posts : 7119
   Posted 9/20/2008 8:55 PM (GMT -7)   

You might be interested in my posting some time ago. I suffered permanent hamstring tendon damage from Levaquin, an antibiotic in the same class as Cipro.



Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 9/21/2008 3:58 PM (GMT -7)   
I am currently on Levaquin. I know the patient information leaflet warns about tendon damage. I am being very careful.

Regular Member

Date Joined Dec 2007
Total Posts : 131
   Posted 9/23/2008 9:24 AM (GMT -7)   
I took two doses of Cipro back toward the end of May.
First dose was before bed. I awoke in the middle of the night with my achilles tendons throbbing in pain. I was awake for part of the night, and finally it subsided and I was able to fall back to sleep.

In the morning, there was no pain and I just wrote it off as one of those weird "Crohn's" inexplicable pains. I took another dose. Throughout the day at work, my feet were terribly sore and throbbing. My ankles swelled up to about twice their normal size. I never took another dose.

Ever since then, I have continued to have swelling and pain in my feet and ankles. I have never had any problems with my feet/ankles before this. I also have severe joint pains and it feels like the tendons in my body are tight and swollen. I get snapping/popping of my tendons in my wrists and elbows and it is quite painful. My fingers and wrists seem to be the worst, along with the elbows.

I have expressed this to 4 doctors now, and all of them insist it could not have been the Cipro, and that it should be out of my system by now. All of my pain and swelling they attribute to my Crohn's, and really won't even listen. They all want to put me on some sort of injectable drugs (methotrexate, remicade, humira, etc. Take my pick apparently? The rheumy mentioned them all.)

I had some mild pain before this Cipro incident, but I was still living a relatively "normal" life. I golfed a couple times a week, walked the dog, was able to do chores and such. All of this has changed. I am basically disabled now. The fact that doctors have been so adamantly opposed to listening to me has really caused a distrust of doctors for me now.
Type I Diabetes- 29 yrs. (MiniMed Insulin Pump)
Celiac Disease- 8 yrs.
Crohn's Disease- (Nov. '06)
No meds at this time. (Don't agree with me.)

Regular Member

Date Joined Aug 2005
Total Posts : 128
   Posted 10/16/2008 10:28 PM (GMT -7)   
We call it getting 'floxed'. In fact, there are thousands of people on a yahoo group called quinolone, and we also have another forum favc which has many people suffering from adverse reactions to cipro. A lot take months to yeras to recover unfortunately. After the very first dose, after 2 hours, I developed;

Bilateral tendinitis in my wrists and my ankles, peripheral neuropathy, chronic sleep onset and sleep maintenance insomnia which lasted 5 months, chronic nightmares lasted 3 months, pulsating tinnitus, tinnitus, swallowing difficulty, muscle pains, eye pains, ear pains, fatigue, blurry vision, static vision, poor night vision, lines in my vision, floaters in my vision, flahses in my vision, poor adjusting from light to dark areas, dry eyes, dry mouth, dry skin, wrinkled skin. Pounding sensations of my neck, heart, stomach, neck. intolerent to caffeine. Joint pains, spider veins. I also cried a lot during the initial first days after I had my reaction.

Oh and I was a very healthy 23 year old male, very fit and ate healthy for the last 6 years, no medical problems at all other than a possible infection. I quit taking cipro after 3 doses and symptoms kept appearing for upto 4 months after I took the last pill. Unfortunately this is typical :(

Before I took cipro I had never had any of those symptoms, I have done karate, judo, boxing 12 years of football, skateboarding, roller hockey, ice skating, climbing... never had any tendon injuries in my life. I also had never experienced insomnia in my life either until the night I took cipro.

The good news is that I recovered and it took me a year, the bad news is there are thousands of people who struggle everyday with symptoms. Even some doctors are dismissing the idea that quinolone caused their tendon issues.

I URGE YOU PLEASE to report your reaction, write to the company that made the drug, report using the yellow card scheme or to the FDA. You have to get these reports in because I feel that the damage from quinolones on tendons is vastly underestimated.
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HDL cholesterol = 39mg/dl
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Post Edited (whoa182) : 10/16/2008 11:32:16 PM (GMT-6)

Okie w/AS
New Member

Date Joined Dec 2010
Total Posts : 1
   Posted 12/30/2010 4:07 AM (GMT -7)   
Hello, I am inquiring about ankylosing spondylitis and ruptured achilles heel tendon. Wondering if anyone knows if it is common to have ruptured AH tendon with AS .  I had kidney failure about 2 years ago and I was given leavequin in hospital for 4 days and on other occasions. So how do I know whether I ruptured the tendon due to AS or leavequin? I also took cipro at this time also.
Thanks and any info is appreciated!

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Date Joined Nov 2003
Total Posts : 7119
   Posted 12/30/2010 3:10 PM (GMT -7)   
I have AS also. Achilles tendon problems are quite common in AS. Repeated bouts of inflammation in the Achilles tendon can lead to calcification of the insertion point of the tendon. Sudden stress on the tendon could cause rupture.

Achilles tendon rupture due to taking Cipro or Levaquin occurs while taking the medication and up to several months later. Your post was unclear as to when you ruptured in relation to taking the meds.

I am sorry this has happened. Have you had a repair yet? How did that go?
Moderator Crohn's disease, Osteoarthritis and Irritable Bowel Forums

CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, pulmonary hypertension, degenerative disc disease, asthma, severe allergy and a host of other medical problems.

Regular Member

Date Joined Oct 2010
Total Posts : 157
   Posted 12/30/2010 3:29 PM (GMT -7)   
I think supplementing magnesium might help take some of the side effects away, but it should be taken after the treatment has been completed not to reduce the effectiveness of the drug. When I was admitted to the hospital 3 weeks ago they gave me Cipro which worked well for my CD, but it came with the down side to it as I got swollen wrists & ankles, blurry vision, joint pain and personality changes. I was on it for 3 days. As soon as I got out I took a big dose of magnesium supplement and it helped a lot with my wrists and ankles which went back to normal within 3-4 days. I'm watching it very carefully for any signs of weakness in my tendons and will try to continue to do so for a few coming months...

Living with CD for 8 years now. In the middle of a flare up.
Currently on 7.5mg Prednisolone. Adverse reaction to AZA
Useless GI. Unfortunately stuck due to geographical limitations. We live on an island...

Forum Moderator

Date Joined Nov 2003
Total Posts : 7119
   Posted 12/30/2010 3:37 PM (GMT -7)   
Magnesium in large doses can cause diarrhea. For some with Crohn's, that only adds to their discomfort. I need magnesium supplementation as mine gets low when I have lots of diarrhea. Replacement via IV does not cause me to have diarrhea. If I need oral replacement, I can only take 1 Slo-Mag a day or I get the big D.
Moderator Crohn's disease, Osteoarthritis and Irritable Bowel Forums

CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, pulmonary hypertension, degenerative disc disease, asthma, severe allergy and a host of other medical problems.

Veteran Member

Date Joined Feb 2009
Total Posts : 1879
   Posted 12/30/2010 3:50 PM (GMT -7)   
This is scary. There is no telling what all some of these drugs have done the unsuspecting public. I was taking levaquin and had a sore achilles tendon. After noticing this, I remembered it was a side effect of this class of medications. It feels better now but is still somewhat tender. It seems once you get sick with a chronic illness, other things also start happening. It makes me wonder.
d 1/09 with colitis sigmoid colon with some diverticular disease as well
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