Crohn's and ASCUS (abnormal pap)?

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Regular Member

Date Joined Mar 2006
Total Posts : 310
   Posted 10/27/2008 8:58 AM (GMT -7)   
Recently, I had an annual gyn exam and have been advised that my pap results were borderline normal/abnormal (nurse's words).  The nurse said that the results showed ASCUS but were negative for HPV.  She said to come back in 3 months for a repeat pap and that this problem is very common, that she calls women all day long about this.  Also, she seemed optimistic about the outcome of the next pap b/c I don't have HPV.
Since my Crohn's is mild, I take only Asacol for maintenance (2 capsules, 3 times a day)... I don't know if Asacol suppresses the immune system or not.  I was on prednisone for a couple of years but came off it about 8 years ago.  I have read elsewhere that women whose immune systems are suppressed can be at higher risk for this outcome, and that it can also occur as a sign of perimenopause which can begin in the late 30s (I'm 37).  I intend to ask my doctor about this when I see her again.
Has anyone else experienced this result?

Regular Member

Date Joined Aug 2008
Total Posts : 107
   Posted 10/27/2008 9:25 AM (GMT -7)   
my pap also came back abnormal again and I do NOT have hpv either. I was thinking it was all the inflamation in my body. I dont know.
 asocol 2- 3 times a day
dr, oharas probotics
vitamin d
multi vitamin
colagon tablets

Veteran Member

Date Joined Aug 2007
Total Posts : 884
   Posted 10/27/2008 11:13 AM (GMT -7)   
There was just a post about this last week, I believe.  Once I started Remicade, mine started coming back atypical for the first time in my life and they were atypical every year that I was on Remicade.  My HPV tests came back negative.  I switched to another biological and this year, it came back normal.  But yes, someone posted a link to an article in a medical journal sometime in the last year or so saying that women on immunosuppresents or biologicals (don't remember for sure which one but it may be immunosuppresents, since I know you said you're not on a biological) were more likely to have atypical paps. 

Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 

Regular Member

Date Joined Mar 2006
Total Posts : 310
   Posted 10/27/2008 5:13 PM (GMT -7)   
Thanks for your replies... Zena, I'll look up that post! I've never been on Remicade but have read/heard quite a lot about it.

Forum Moderator

Date Joined Nov 2003
Total Posts : 7119
   Posted 10/27/2008 8:32 PM (GMT -7)   
Here is the link to an article that discusses women with inflammatory bowel disease being more likely to have abnormal PAP smears:
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

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