I was on Humira from last Feb til the first of Nov. It never really seemed to help that much. I did get fatigue and headaches after each injection.
After my GI upped my dosage to one injection per week, I did get a bit better relief from the CD symptoms, but after my third or fourth weekly dose I had such extreme fatigue I couldn't get out of a chair. GI discontinued humira after that.
I've been doing a bunch of research on anti TNF's (Remicade, Humira, Cimzia, Tysabri, etc), and unfortunately the total percentage of CD sufferers that get relief from Anti TNF's is not very high. It depends on the med and study you look at, but it averages out to right around half.
I started Cimzia four days ago. I'm going to give it two months. If I don't get a *very good* response from it, I'm not going to continue it like I did Humira. I never felt like Humira did enough good to make up for it's side effects.
Just trying to be a "Regular Member".
Entocort 9 mg/day, Prednisone 20 mg/day, started Humira 1/22/08, started 100 mg of Azasan (Imuran) 2/20/08. Increased Azasan to 150 mg 10/15/08. Discontinued Humira 11/03/08 after extreme fatigue and moderate muscle aches. Started Cimzia 12/4/08.
I'm convinced that Prednisone is the root of all evil, and primarily responsible for global warming.