will failed drugs work after surgery

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Regular Member

Date Joined Jun 2008
Total Posts : 167
   Posted 1/1/2009 10:01 AM (GMT -7)   
I thought some of you may know about past failed drugs working later.

I was on Imuran and Humira before my surgery. Obviously these did not work at that time. Does that mean they won't work for me now too? Or are they worth trying again to see?
Has anyone failed a drug and then tried it later on and have it work for them? I am really hoping that they just didn't work because my crohn's was so aggressive at the time.

I haven't got the results of my recent CT yet because my surgeon went on vacation for the holidays (I should get them tomorrow) but my symptoms seem to be pointing to Crohn's still being active. (which really sucks becuase I was really hoping for remission again like last time). I am actually having more pain now than I did before surgery and was very close to going to the ER last night becuase of it, and I avoid the ER at all costs....

I am really hoping that I can just start over again with Imuran and have it work or even the Humira.

Any thoughts?
Dx with Crohn's in 1997 after 5 years of worsening symptoms.
Resection a few months after dx after 1 month on TPN and IV steroids.
Resection October 2008.
Also have severe asthma.

Tried: Pentasa, Cholestyramine

Presently taking: now on 35 mg prednisone, probiotics, calcium, B12.
For asthma I take Advair 500, singulair, arieus

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 1/1/2009 10:24 AM (GMT -7)   
I was on Asacol before my last resection and afterwards the GI I had at the time said I no longer needed it. Well I started feeling sick again shortly after stopping it, so I went back on it, and with in no time I was feeling better. I saw give it a try, its best to try to keep the inflammation down.

Good luck!
Moderator for Anxiety/Panic Forum
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, and Calcium and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia and Osteoarthritis and Anxiety. Currently my Crohns is in remission.

Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 1/1/2009 7:01 PM (GMT -7)   
Westat- Good question. I don't know the answer but any responses will be interesting. As for your pain your body is still adjusting from your surgery. I would give the surgeon a follow up call/visit to make sure you don't have a secondary infection building. I wouldn't think you should be hurting worse than you did prior to surgery! This type of surgery is such a major shock to your system sometimes it takes months before you truely straighten out. Hope you're feeling better soon.
Dx'd Jan'06, 1st Resection 7/06, Humira, Imuran, B12 injections, Nexium, Lexapro, Nulev, Glucosamine, Multi-Vitamin, Calcium Citrate, Ultracet. Secondary conditions: Psorasis, Osteoarthritis, Fibromyalgia, Lactose Intolerant, gallstones, kidney stones & peri-menopausal.

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