Question about Tramadol

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Regular Member

Date Joined Nov 2007
Total Posts : 147
   Posted 1/9/2009 8:41 AM (GMT -7)   
Does anyone have any idea why Tramadol would be reducing fevers when Tylenol does nothing?  I was given a prescription for Tramadol that contains acetaminophen to help with pain in my feet from arthritis.  Supposedly I do not have inflammatory arthritis just the kind that you get from Crohn's/UC sometimes.  What is strange is that I often run temps ranging from 99 to 101 on a fairly regular basis.  I can usually tell that my temp is up because I get that icky fever feeling but taking tylenol does nothing to lower my temp.  So I started thinking that maybe I just have a higher body temp.  But now I have been noticing when I take the Tramadol my temp goes down to 98.6 or lower.  I know Tramadol is not an anti-inflammatory so I am really confused as to why my body temp goes down when I take it especially since tylenol (acetaminophen) does nothing. 

Veteran Member

Date Joined Jul 2005
Total Posts : 733
   Posted 1/9/2009 1:48 PM (GMT -7)   
That's a tricky question, Veebo. I googled around on the internet, but I really didn't find anything helpful. Here's what I'm thinking...

The narcotic effect of the tramadol calms your body down in addition to helping with pain... Maybe it calms your digestive tract, which in turn calms your fever? In that sense, the acetominaphen in it is sort of pointless. I know that sometimes even taking a sleeping pill helps my guts because it puts THEM to sleep as well... maybe it's the same sort of deal?

Another possibility is that the difference in efficacy is related to a difference in "binders" or "fillers" in the different pills. Maybe the tramadol has a special binder that helps it be absorbed in a certain way? That might help the tylenol be absorbed too... You might ask your pharmacist, if you have a good one.

I'm curious now, so if you piece this one together let me know!
27f, dx'd CD July '05 after 6 fistula/abscess surgeries
(miscarried at 13 weeks, now waiting to heal before trying again)
Stopped Humira August 22nd, 2008.
Went Gluten-Free, noticing some definite improvement.
Started LDN October 27th, and already LOVING IT.

"Our greatest fear is not that we are inadequate, but that we are powerful beyond measure."

Regular Member

Date Joined Nov 2007
Total Posts : 147
   Posted 1/9/2009 8:19 PM (GMT -7)   
Thanks for your thoughts on this patientspiders. I am actually seeing my GI next week so I am going to ask him about it. My mother thinks it might be related to me being stressed out by the pains which is causing me to run a fever and that the narcotic effect of the tramadol relaxes me. However, I don't really think or feel that I stressed out. I also never ran fevers when I was on prednisone. My thoughts were that maybe tramadol was acting like an anti-inflammatory but everything that I have read says otherwise.

Veteran Member

Date Joined Dec 2006
Total Posts : 559
   Posted 1/10/2009 12:38 PM (GMT -7)   
I really don't know why Tramadol seems to be suppressing your fever. A bigger question is why you're running a constant low-grade fever. In fact, I used to have that problem and it turned out to be from fistulas. The fevers got cured after I had a bowel resection in which the obstructed fistula-ridden section of intestine was removed. Fortunately, the fistulas have not recurred, though the obstruction has.

Also, be a little careful on using the Tramadol. It's good for pain, but can be addictive if you take it too frequently or for too long. Definitely don't use it as a substitute for an anti-inflammatory drug.

best regards,
Crohn's since 1988
3 resections

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