I've been on Pentasa for about 4 years now. My GI says it's not even necessary for me to be on it since I'm on the 'cade now, but I never like to solely depend on one drug. However, over the holidays I experimented with taking fewer, and finally with taking none. My results were the rectal burning I've had for three years (and thought was residual fissure pain) was all but gone. However, after a few days my stool got hard and dry and was hard to pass. I tried to drink more water (up to 3 liters) ad eat more fruit and veggies (which I already eat plenty of) but nothing helped. Yesterday I went back to my full dose and this morning I burned like fire.
Sound familiar? Any help out there?
Bad fissure Feb 2005, still have it January 2006. On Pentasa and Imuran 100mg. Some slight swelling and ulceration of terminal ileum. No other symptoms. Now on Remicade!