Hey! I think patientspider has definitely made some good points. You really have to know a lot about
your disease, about
the medicines that are out there and about
how every decision you make about
your CD affects your life.
I have a few pieces of advice for you. Before you decide whether you want to take Imuran or Humira make your doctor do this genetic test for Imuran. This genetic test shows if your body would block Imuran I guess. It's still not a guarantee that Imuran will work for you since only 30-40% percent of people respond to Imuran, but there's no point of you taking it if this genetic test proves that Imuran isn't for you. I have no idea how it's called, I just know I had it and it came out ok, I started taking Imuran, haven't had any big side-effects minus the fact that my leukocytes are under the normal level. I started with 100mg and waited for about
3 months and it wasn't really helping so we increased it to 125mg (it all depends on how much you weight) and it started working. We were patient and I'm so glad that we didn't switch to Remicade right away.
For me Imuran made a huge difference, it kept me from having a surgery yet, I have a stenosis but it's doing pretty ok now! The only thing that Imuran didn't fix for me is my anal canal inflammation, which is why now I have to choose between Humira and Remicade, after being on Imuran for 2.5 years. Imuran is a powerful drug, it really is and it's no joke...but those are pills and it's definitely easier to live with pills (but then again "easy" is relative since Humira doesn't take much of your time). If you choose Imuran please know that it might make you feel sick - some people can't deal with it, others say you have to overeat yourself before taking it and that you won't throw up then, and some people like me take Pantoprazole in the morning.
Humira is a powerful drug too, it can help you so much. But just like patientspider I put it at the top of my pyramid list. I've always thought that Humira/Remicade would be my last resort since there isn't anything else after that and life is long. But sometimes you just can't have it the way you want it. All in all...just do this genetic test and then make your decision. I hope everything goes well!
:) Be strong
21 yr. old with crohn colitis. First symptoms in June 2003, diagnosed in March 2004. Been in remission on mesalazine till June 2006 (actually till January) and then on steroids and Imuran. Currently taking Imuran and metronidazole (was taking ciprofloxacine for a month and then switched to metronidazole). No surgeries so far.
Post Edited (caroline_r) : 1/24/2009 11:48:25 AM (GMT-7)