How long on methotrexate...?

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Regular Member

Date Joined Mar 2008
Total Posts : 382
   Posted 1/27/2009 2:03 AM (GMT -7)   
In helping to decide whether or not to have surgery, I was wondering how long has anybody been on metho? I was on 25mg. injections once a week for four months and now reduced to 15mg. I suppose it is not really considered a maintenance drug?
My GI referred me to colorectal surgeon who I am seeing on Wednesday.
55 yr. old F dx. CD 07/07
Was on prednisone for three months but no medication for next 11 months.
 Started weekly methotrexate injections 09/22/08.

Regular Member

Date Joined Dec 2007
Total Posts : 414
   Posted 1/27/2009 5:47 AM (GMT -7)   
I've been on it well over 6 years now, 25mg tablets once a week. It reduced a lot of my inflammation in 3 months but didn't quite get me better so they boosted it with an infliximab which got me 100% better and the methotrexate maintained that, they tried dropping me down to 15mg and I got sick within a couple of months so they put it back up to 25mg and have left it like that ever since. But from the way my gastro and rheumo talk they have had people on it for over 10 years so in my nhs trust its definitley considered a maintenence drug, I guess it depends on how well they think its working for you.

Veteran Member

Date Joined Apr 2004
Total Posts : 1200
   Posted 1/27/2009 6:43 AM (GMT -7)   
I've been on 25mg. for the past 4 years and my dr. has no plan to take me off it.

New Member

Date Joined Dec 2008
Total Posts : 7
   Posted 1/27/2009 6:50 AM (GMT -7)   
I was on it for about 4mo before i started to loose my hair. They now have taken me off it.

Veteran Member

Date Joined Jul 2006
Total Posts : 6927
   Posted 1/27/2009 8:01 AM (GMT -7)   
I have been on 25 mg injection for 2 1/2 years and I just went down to 20 mg last week.
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Rider Fan
Veteran Member

Date Joined May 2008
Total Posts : 1445
   Posted 1/27/2009 9:33 AM (GMT -7)   
cj2mama said...
I was on it for about 4mo before i started to loose my hair. They now have taken me off it.
Is hair loss a big concern?  Maybe it's different for me since I'm a male, but I'd trade my hair in a second for remission.  I told my doc about some hair falling out and he didn't seem concerned.  I take 1.5mg of folic acid a day except for the day of the injection.  I think it mtx works better when I take less folic acid.

Dx'ed in 1999. No surgeries.

Current meds: 25mg Methotrexate. 12.5mg prednisone. Udo's Choice Probiotics (30 billion).

Tried SCD, didn't work, now avoiding gluten and dairy.

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