Anyone else experience horrible body oder caused by colonoscopy prep?

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Date Joined Aug 2006
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   Posted 3/5/2009 8:26 PM (GMT -7)   
OK, I'm sorry if this is a bit graphic, but I'm wondering if anyone else has experienced this. If I have to do a colonoscopy prep or I have severe diarrhea, I develop an exceptionally unpleasant body odor during the course of the diarrhea that does not dissipate until 24 hours later (or even 36 hours later if the diarrhea was really severe). Luckily this does not happen more than a handful of times per year at most, but it is a real social embarrassment when it does, since showering, etc., has no affect on the smell; it only goes away with time. I wondered if this happens to anyone else, or if I am uniquely unlucky (maybe some mild metabolic disorder?). Thanks for your insight.

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   Posted 3/5/2009 9:09 PM (GMT -7)   
Not had this with colonoscopy prep but I just got off a 10 day course of doxycycline for a sinus infection - that stuff made me reek! Worse odor and it hung on for 2 days after the last dose. It was especially bad if I had night sweats which I do most night thanks to lupus. Yuck...
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CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

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   Posted 3/5/2009 11:55 PM (GMT -7)   
Ive never experienced odor with prep, however when I was on pred I swore I could just smell body oder constantly.  I think it was from sweating all the time.  It made me sick to my stomach.

Dianogsed with Crohns: At 16 years old. 22 years old now.
Surgeries:2 Bowel Resections, Gallbladder Removed.
Current Meds: Humira (bi-weekly)

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   Posted 3/6/2009 11:54 AM (GMT -7)   
Never experianced anything like that in my entire 18 yrs of having this DD.

My bum is broken....there's a big crack down the middle of it! LOL :)

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   Posted 3/6/2009 12:19 PM (GMT -7)   

Thanks for the replies, all. It is beginning to look like I am uniquely unlucky in this respect. However, more input welcomed if anyone else wants to weigh in.

Regarding the smell itself, Loobylou, I wish it did smell like ammonia or sweat, that would be much better. It smells basically like diarrhea but worse. Ides, I hope the smell you got from doxycycline wasn't like this.

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Date Joined Feb 2009
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   Posted 3/6/2009 1:06 PM (GMT -7)   
I always experience especially stinkiness after the test.
Crohn's Disease - 29 years
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   Posted 3/6/2009 3:37 PM (GMT -7)   
The stress from the prep makes me perspire.
I basically reek the evening before...
The old preps made me smell like vinegar...
Miralax just like sweat.
diagnosed 1981
remission until 2006
Entocort, 6mp,Hydrochlorothiazide
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   Posted 3/6/2009 4:32 PM (GMT -7)   
The smell has not yet disappeared so I don't think it was the doxycycline. It must be one of the other new meds they have me on. Either that or it is a chemical reaction between two of my medications. Anyone know a chemist to unravel this?

At the height of the lupus onset when I had massive, change the nightie 3 times, night sweats, there was never much odor. The night clothes would get sour smelling if not washed and dried promptly.

The odor now is very acrid and chemical smelling. It makes me nauseous. I want it to go away!!!
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CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

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Date Joined Oct 2004
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   Posted 3/6/2009 5:35 PM (GMT -7)   
I never had such a thing when doing prep, but it is noticeable problem for me that when I have sweats that I develop an acrid body odour. Of course living on my own I don't smell it sometimes, until I go out and come back again - at which point I feel sorry for the people I've been dealing with. It's a sour, vinegary smell; I assume it is an overdose of the chemical that the biochemists have reported as isolating from sweat, that is the basic ingredient of sweaty socks odour.
I'm drinking lemon in water, in the hopes that whatever component of sweat is causing it would normally be broken down by the liver, and the help that lemon (and water) gives to the liver's functioning will help eradicate it.
On a bad day I have been known to throw out clothes because the smell won't go, but I've never been as unlucky as you Writer ! Have you given any thought to your skin bacteria colonies ? Have you perhaps been soaping excessively, leading to a bacterial monoculture that may express sulfides ?
When it comes to drug interactions, this is a very...interesting, eyes and under-researched problem. There have been instances of patients in ER actually not only smelling of chemicals, but actively emitting an unidentified gas, through the skin or wounds, that was so toxic that it forced the closure and evacuation of the clinic. This happened in a matter of minutes ! A full HAZMAT decontamination was required. As the patients died in each case (as I think may have some of the ER staff) it was never possible to work out what was happening chemically, or even what other licit or illicit substances may have been ingested. Plain fact of the matter is, there is no telling what the chemical factory that is our body will do under certain conditions, and with medications we may stray into unknown territory. Cheery thought.

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   Posted 3/7/2009 8:42 PM (GMT -7)   
For those with ammonia or vinegar-smelling sweat, I thought the following was kind of interesting (the source is this article:

"Our body odour is dependant on the constituents of the sweat produced by the apocrine (sweat) glands....The sweat contains steroid compounds, especially the 16-androstenes — these are particularly profuse in the sweat produced by the groin and armpits. Once bacteria have acted on the sweat they break it down and that gives it its individual smell.

The more androstene that a person’s sweat contains, the greater the potential for him or her to be strong smelling. It has been found that two of the 16-androstene compounds are important in this respect. If there is a predominance of androstenol, the sweat from the armpits and kindred areas tends to smell markedly musky; if there is a predominance of androstenone, the sweat develops an obvious smell of urine."

This makes me wonder if those using steroids might be more liable to having smelly sweat, since sweat contains steroid compounds in the first place, and now more of those steroids might be available to the body. However, I have no idea if that is biologically plausible.

Snohare, I doubt the problem is from bacteria on the skin in my case, as I never get an odd smell just from sweating. I'm guessing that I might be deficient or partially deficient in one or more of the enzymes in the small intestine involved in the digestion of sugars or starches, but which enzyme or enzymes I have no idea. (Maybe something like trimethylaminuria, in which people lack the enzyme to break down trimethylamine, and therefore it builds up in the body and is released in breath and sweat and causes a perpetual fishy odor.) At least I'm lucky this only happens rarely, and not all the time!

Thank you all for your input.

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Date Joined Oct 2004
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   Posted 3/8/2009 11:03 AM (GMT -7)   
I see you've been doing your homework, Writer ! eyes There's nothing like being motivated to propel research is there...and if you are a writer then I guess that anything is better than facing that dreaded blank white sheet...! smilewinkgrin
If the problem is lack of enzymes, have you tried taking digestive enzymes as a supplement ? I know you can get them (I'm about to go onto them myself) and I would guess that like any other product field there will be more than one variety; once you start finding out why they differ, you are likely to find mention of problems such as yours if that is pertinent.
nono Cruel and unusual though your body odour problem is, it could be worse. When I was a teenager my mother kept a boarding house and one of our lodgers was a chap in his 20s, with a big problem. It dominated his life, it was a real cross to bear for him; it shaped his entire life, literally leading him to anxiety, depression, and despair. He had sweaty feet and nothing he tried could ever extinguish the smell. It was constant and unremitting, no mercy could he find. Since then I have read of the rare malady he had and that there is now a simple procedure that cures it - but back then, in the end, my mother (as so many before her) asked him to leave, because she was afraid the smell would get into the furnishings. I sometime think of that poor man, wandering the world like a sweaty-footed Flying Dutchman... shakehead
Sometimes I think that life is so bizarre, you could not invent it ! yeah

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Date Joined Dec 2011
Total Posts : 22
   Posted 6/30/2014 5:05 PM (GMT -7)   
Hi everyone I have had a horrible smell on my body for many years, and I just fixed my problem. It was from Hyperparatharoidism which causes multiple organs to stop working properly. In my case it was my colon and kidney's. When something is wrong in the body (imbalance of any kind) it throw's off the chemistry. Colon related problems come from contamination and the death of your probiotics (they kill all of the bad bacteria in your colon). It is my opinion that somehow your intestinal walls get completely cleaned out and all of your probiotics are dying as a result of your colonoscopy. candida takes over and your colon walls became permeable. (leaky gut syndrome). I had it. but now I am good. Please buy probiotics and take one a day possibly (50billion culture's strength). Or eat real Greek yogurt its the best. Also stay away from sweet stuff (it feeds bacteria and candida). Good luck.
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