Why do TNF blockers stop working?

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Regular Member

Date Joined Mar 2009
Total Posts : 52
   Posted 3/10/2009 7:34 PM (GMT -7)   
Here is a question that deserves some consideration, 
Why do TNF blockers eventually stop working in some patients? 
To me this indicates that their must be something else triggering the disease such as a bacteria or some allergic reaction.  Any thoughts on this?  

Rider Fan
Veteran Member

Date Joined May 2008
Total Posts : 1445
   Posted 3/10/2009 7:37 PM (GMT -7)   
They stop working because your body develops antibodies to the anti TNF protein, making it useless. This is less of a problem supposedly with Humira/Cimzia since it's human based not mouse based.
32 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira. 22.5mg prednisone. Udo's Choice Probiotics (30 billion).

Tried SCD, didn't work, now avoiding gluten and dairy.

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