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Regular Member

Date Joined Oct 2008
Total Posts : 79
   Posted 3/11/2009 3:14 AM (GMT -7)   
is it common with crohn's disease to have slightly elevated liver enzymes?? has anyone else had this when they have had blood tests taken? it has shown up in mine about 3 times? i don't drink and i dont have hepatitis?

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 3/11/2009 6:51 AM (GMT -7)   
What meds are you on? Some meds can cause the increase in liver enzymes.
Gail*Nanners* Co-Moderator for Anxiety/Panic Forum
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, and Calcium and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia and Osteoarthritis and Anxiety. Currently my Crohns is in remission.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined Aug 2007
Total Posts : 884
   Posted 3/11/2009 10:34 AM (GMT -7)   
Mine frequently get elevated and will stay that way for a while and then go back down.  I've had ERCPs, MCRPs, liver biopsies, etc. done and they only showed that my bile ducts were inflamed.  We just keep testing periodically and they always go back down. They thought last time maybe it was the 6mp, but they were elevated before I even started it and the levels went back to normal while I was still on it.  Since stopping it, though, my enzymes have been normal. 

Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 

Veteran Member

Date Joined Mar 2005
Total Posts : 1289
   Posted 3/11/2009 10:37 AM (GMT -7)   
my doc took me off asacol bc the combo of that and 6-mp got my liver #'s really out of whack...they started dropping when i quit the asacol...i think prednisone can affect levels also.

Regular Member

Date Joined Oct 2008
Total Posts : 79
   Posted 3/11/2009 7:04 PM (GMT -7)   
i'm taking salofalk granules. i know they can cause some liver problems but ur not meant to stay on them if they do, and my GI doesnt think it's do with the meds, cos if it were then he would take me off them. so yeh i dunno if it's something that happens with crohn's or what?

Veteran Member

Date Joined Feb 2009
Total Posts : 529
   Posted 3/11/2009 7:16 PM (GMT -7)   
My doctor ran some liver tests on me yesterday, I don't have the results yet but she seemed concerned and had to take me off of Pentasa. I wouldn't be surprised if mine were out of whack as well. Your doctor should try you on different meds and see if they go back to normal in my opinion :/

New Member

Date Joined Dec 2008
Total Posts : 5
   Posted 3/11/2009 9:38 PM (GMT -7)   
My liver enzymes started showing up elevated when I was on 6-MP so I went on and off of that for a while. They kept being elevated so I finally had a liver biopsy done which showed I have Alpha-1 Antitrypsin deficiency. It's an enzyme deficiency (I can't explain it, try google). So anyways, since the biopsy my lab tests have been "normal" and my doc says there's nothing to worry about. I didn't know there were others out there that had elevated liver enzymes. Some times I feel like I'm on an island, ya know? Just make sure you keep an eye on it though.
*24 years old, female* *Diagnosed with Crohn's October 2006* *Diagnosed with Alpha-1 Anti-Trypsin Deficiency July 2008* *Also, I have had psoriasis (no meds have EVER worked-not even crohn's meds or pred., but tanning 2-3x/wk keeps the "scales" away) since I was 5 and I am anemic* *Currently taking Humira with mild side effects but at least it's the only one and I can eat again without emptying my bowels every hour or so* *Previous meds: Asacol, Cipro, Lialda, Prednisone, 6-MP* *Also taking daily vitamins: multi, iron, folic acid, c, flaxseed oil, and fish oil*
*"True strength is being able to hold it all together when everyone else is expecting you to fall apart" -unkown*
*"I am not afraid, I was born to do this" -Joan of Arc

Regular Member

Date Joined Oct 2008
Total Posts : 79
   Posted 3/11/2009 11:54 PM (GMT -7)   
yeh i know what u mean about feeling like ur alone! it's like u imagine that no one else has the same symptoms etc... but yeh my GI said he's keeping an eye on it more than worrying about it at the moment!
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