Amitriptyline to treat diarrhea

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New Member

Date Joined Aug 2007
Total Posts : 18
   Posted 3/12/2009 5:19 PM (GMT -7)   
I had bowel resection surgery two years ago. They removed most of my colon and 18" of small bowel. Since surgery, I have severe diarrhea. The colon absorbs water so without the colon, there is nothing to absorb the water which results in diarrhea. I've tried imodium, questran, keopectate etc. My doc has recently prescribed the anti-depressant Amitriptyline. I'm told one of the side affects is constipation so it should help to bulk up my stool. I've been very reluctant to try this new med as I don't want to feel out of it, groggy etc. Is anyone taking this med and has it helped with diarrhea? My doc also prescribed codiene which is an addictive drug? I'm told it should also help with the diarrhea. I haven't tried either drug yet and am hoping to get some feedback before I decide. My doc says to try the amitriptyline first and see how that goes. Any advice is greatly appreciated.

Regular Member

Date Joined Dec 2008
Total Posts : 23
   Posted 3/12/2009 8:15 PM (GMT -7)   
Hi gmd... I have been given Amitripline for help with mild pain and sleep distrubances. I am not sure it helps at all with diarrhea because I have had D for the last 2 years almost constantly since being on ami... i hope this helps
I am a 45 year old Canadian, living in Northern Ontario. Just recently diagnosed with Crohn's and Colitis Nov '07 ... Had a Gastric Bypass Surgery in Feb '08

Elite Member

Date Joined Feb 2004
Total Posts : 20577
   Posted 3/12/2009 8:43 PM (GMT -7)   
Sorry to hijack your thread gmd...but kemperca I read in your sig line that you were DX with crohn's and colitis, I have crohn's colitis which is actually crohn's affecting the colon (where ulcerative colitis typically hangs out) but it's still crohn's and so many CDers get confused when their docs throw the word "colitis" out there leaving the patient to think they have both UC and CD when really it's their CD affecting their colon and not's estimated that 2% of patients suffer with both UC and CD which is fairly low.

gmd, I hope you find relief and that the Amitriptyline does the trick for you.

My bum is broken....there's a big crack down the middle of it! LOL :)

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